Nd

YAG laser thermocoagulation of the prostate: the barbecue effect.

Eduardo Orihuela, M. Pow-Sang, T. Cammack, M. LaHaye, D. F. Cowan, M. Warren

Research output: Contribution to journalArticle

Abstract

OBJECTIVE: To determine systematically the depth of coagulation necrosis induced during Nd: YAG laser irradiation in the canine prostate model, and to define the correlation of laser dose with depth of the lesions. METHODS: We investigated the effect of various dosimetries on prostatic tissue of 17 mongrel canines using laser power in the range of 8 to 60 watts (W) at varying exposure times, from 20 to 300 seconds (S). Applied energy ranged from 1,000 to 5,500 Joules (J). RESULTS: Three distinct features were observed. First, deep coagulation necrosis was induced only with laser regimens of > or = 2,100J, suggesting that there is a threshold of energy that must be overcome in order to achieve significant coagulation depth. Second, the deepest coagulation necrosis was achieved with a low power slow-heating regimen (15W X 180S). Tissue surface changes appeared to be responsible for the reduced depth of coagulation necrosis seen with higher power regimens (> 20 W). Third, increasing the energy above 3,600J did not augment the depth of coagulation, suggesting that a steady state for temperature distribution is reached at that rate of heating. CONCLUSIONS: Our study suggests that in the canine prostate, a low power slow-heating regimen of 15W X 180S may yield larger volumes of coagulation necrosis than other regimens.

Original languageEnglish (US)
Pages (from-to)212-215
Number of pages4
JournalArchivos Espanoles de Urologia
Volume48
Issue number2
StatePublished - Mar 1995

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Laser Coagulation
Solid-State Lasers
Prostate
Necrosis
Heating
Canidae
Lasers
Temperature

ASJC Scopus subject areas

  • Urology

Cite this

Orihuela, E., Pow-Sang, M., Cammack, T., LaHaye, M., Cowan, D. F., & Warren, M. (1995). Nd: YAG laser thermocoagulation of the prostate: the barbecue effect. Archivos Espanoles de Urologia, 48(2), 212-215.

Nd : YAG laser thermocoagulation of the prostate: the barbecue effect. / Orihuela, Eduardo; Pow-Sang, M.; Cammack, T.; LaHaye, M.; Cowan, D. F.; Warren, M.

In: Archivos Espanoles de Urologia, Vol. 48, No. 2, 03.1995, p. 212-215.

Research output: Contribution to journalArticle

Orihuela, E, Pow-Sang, M, Cammack, T, LaHaye, M, Cowan, DF & Warren, M 1995, 'Nd: YAG laser thermocoagulation of the prostate: the barbecue effect.', Archivos Espanoles de Urologia, vol. 48, no. 2, pp. 212-215.
Orihuela E, Pow-Sang M, Cammack T, LaHaye M, Cowan DF, Warren M. Nd: YAG laser thermocoagulation of the prostate: the barbecue effect. Archivos Espanoles de Urologia. 1995 Mar;48(2):212-215.
Orihuela, Eduardo ; Pow-Sang, M. ; Cammack, T. ; LaHaye, M. ; Cowan, D. F. ; Warren, M. / Nd : YAG laser thermocoagulation of the prostate: the barbecue effect. In: Archivos Espanoles de Urologia. 1995 ; Vol. 48, No. 2. pp. 212-215.
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