Necrotizing pancreatitis

Challenges and solutions

Victoria A. Bendersky, Mohan K. Mallipeddi, Alexander Perez, Theodore N. Pappas

Research output: Contribution to journalReview article

7 Citations (Scopus)

Abstract

Acute pancreatitis is a common disease that can progress to gland necrosis, which imposes significant risk of morbidity and mortality. In general, the treatment for pancreatitis is a supportive therapy. However, there are several reasons to escalate to surgery or another intervention. This review discusses the pathophysiology as well as medical and interventional management of necrotizing pancreatitis. Current evidence suggests that patients are best served by delaying interventions for at least 4 weeks, draining as a first resort, and debriding recalcitrant tissue using minimally invasive techniques to promote or enhance postoperative recovery while reducing wound-related complications.

Original languageEnglish (US)
Pages (from-to)345-350
Number of pages6
JournalClinical and Experimental Gastroenterology
Volume9
DOIs
StatePublished - Oct 31 2016
Externally publishedYes

Fingerprint

Pancreatitis
Necrosis
Morbidity
Mortality
Wounds and Injuries
Therapeutics

Keywords

  • Necrotizing pancreatitis
  • Pancreatic collections
  • Pancreatic debridement
  • Pancreatic necrosectomy
  • VARD

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Necrotizing pancreatitis : Challenges and solutions. / Bendersky, Victoria A.; Mallipeddi, Mohan K.; Perez, Alexander; Pappas, Theodore N.

In: Clinical and Experimental Gastroenterology, Vol. 9, 31.10.2016, p. 345-350.

Research output: Contribution to journalReview article

Bendersky, Victoria A. ; Mallipeddi, Mohan K. ; Perez, Alexander ; Pappas, Theodore N. / Necrotizing pancreatitis : Challenges and solutions. In: Clinical and Experimental Gastroenterology. 2016 ; Vol. 9. pp. 345-350.
@article{35996fcb111944de854394cfc5f3e1ba,
title = "Necrotizing pancreatitis: Challenges and solutions",
abstract = "Acute pancreatitis is a common disease that can progress to gland necrosis, which imposes significant risk of morbidity and mortality. In general, the treatment for pancreatitis is a supportive therapy. However, there are several reasons to escalate to surgery or another intervention. This review discusses the pathophysiology as well as medical and interventional management of necrotizing pancreatitis. Current evidence suggests that patients are best served by delaying interventions for at least 4 weeks, draining as a first resort, and debriding recalcitrant tissue using minimally invasive techniques to promote or enhance postoperative recovery while reducing wound-related complications.",
keywords = "Necrotizing pancreatitis, Pancreatic collections, Pancreatic debridement, Pancreatic necrosectomy, VARD",
author = "Bendersky, {Victoria A.} and Mallipeddi, {Mohan K.} and Alexander Perez and Pappas, {Theodore N.}",
year = "2016",
month = "10",
day = "31",
doi = "10.2147/CEG.S99824",
language = "English (US)",
volume = "9",
pages = "345--350",
journal = "Clinical and Experimental Gastroenterology",
issn = "1178-7023",
publisher = "Dove Medical Press Ltd.",

}

TY - JOUR

T1 - Necrotizing pancreatitis

T2 - Challenges and solutions

AU - Bendersky, Victoria A.

AU - Mallipeddi, Mohan K.

AU - Perez, Alexander

AU - Pappas, Theodore N.

PY - 2016/10/31

Y1 - 2016/10/31

N2 - Acute pancreatitis is a common disease that can progress to gland necrosis, which imposes significant risk of morbidity and mortality. In general, the treatment for pancreatitis is a supportive therapy. However, there are several reasons to escalate to surgery or another intervention. This review discusses the pathophysiology as well as medical and interventional management of necrotizing pancreatitis. Current evidence suggests that patients are best served by delaying interventions for at least 4 weeks, draining as a first resort, and debriding recalcitrant tissue using minimally invasive techniques to promote or enhance postoperative recovery while reducing wound-related complications.

AB - Acute pancreatitis is a common disease that can progress to gland necrosis, which imposes significant risk of morbidity and mortality. In general, the treatment for pancreatitis is a supportive therapy. However, there are several reasons to escalate to surgery or another intervention. This review discusses the pathophysiology as well as medical and interventional management of necrotizing pancreatitis. Current evidence suggests that patients are best served by delaying interventions for at least 4 weeks, draining as a first resort, and debriding recalcitrant tissue using minimally invasive techniques to promote or enhance postoperative recovery while reducing wound-related complications.

KW - Necrotizing pancreatitis

KW - Pancreatic collections

KW - Pancreatic debridement

KW - Pancreatic necrosectomy

KW - VARD

UR - http://www.scopus.com/inward/record.url?scp=84995553794&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84995553794&partnerID=8YFLogxK

U2 - 10.2147/CEG.S99824

DO - 10.2147/CEG.S99824

M3 - Review article

VL - 9

SP - 345

EP - 350

JO - Clinical and Experimental Gastroenterology

JF - Clinical and Experimental Gastroenterology

SN - 1178-7023

ER -