Necrotizing pancreatitis: Challenges and solutions

Victoria A. Bendersky, Mohan K. Mallipeddi, Alexander Perez, Theodore N. Pappas

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations


Acute pancreatitis is a common disease that can progress to gland necrosis, which imposes significant risk of morbidity and mortality. In general, the treatment for pancreatitis is a supportive therapy. However, there are several reasons to escalate to surgery or another intervention. This review discusses the pathophysiology as well as medical and interventional management of necrotizing pancreatitis. Current evidence suggests that patients are best served by delaying interventions for at least 4 weeks, draining as a first resort, and debriding recalcitrant tissue using minimally invasive techniques to promote or enhance postoperative recovery while reducing wound-related complications.

Original languageEnglish (US)
Pages (from-to)345-350
Number of pages6
JournalClinical and Experimental Gastroenterology
StatePublished - Oct 31 2016
Externally publishedYes


  • Necrotizing pancreatitis
  • Pancreatic collections
  • Pancreatic debridement
  • Pancreatic necrosectomy
  • VARD

ASJC Scopus subject areas

  • Gastroenterology


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