Neoadjuvant use of ipilimumab in locally advanced melanoma

Lynn J. Howie, Douglas S. Tyler, April K.S. Salama

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Recent advances in immune modulating therapies show great promise for patients with advanced melanoma, however optimal strategies for achieving long-term disease control in locally advanced melanoma are unclear. We present two cases of neoadjuvant ipilimumab, one case in combination with isolated limb infusion (ILI) followed by surgical resection and one followed by surgery alone. Both patients have had durable responses. These cases highlight the ongoing need for prospective trials in the neoadjuvant setting.

Original languageEnglish (US)
Pages (from-to)841-843
Number of pages3
JournalJournal of Surgical Oncology
Issue number8
StatePublished - Dec 15 2015
Externally publishedYes


  • immunotherapy
  • ipilimumab
  • melanoma
  • neoadjuvant

ASJC Scopus subject areas

  • Surgery
  • Oncology


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