Neuro-ophthalmologic manifestations of cholangiocarcinoma: A case series

G. Rico, S. V. Smith, Yusra Siddiqui, A. Whyte, D. Gombos, A. G. Lee

Research output: Contribution to journalArticle

Abstract

PurposeTo describe the neuro-ophthalmologic findings of cholangiocarcinoma.MethodsWe report a retrospective chart review of cholangiocarcinoma patients presenting at two tertiary care centers in the Texas Medical Center.ResultsFive patients with neuro-ophthalmologic symptoms related to cholangiocarcinoma were identified. One patient presented with diplopia due to metastasis to the left medial rectus muscle, two patients had metastasis to the occipital lobe resulting in homonymous hemianopsia, one patient had involvement of the clivus resulting in sixth nerve palsy, and one presented with a hypercoagulable state-related stroke causing a homonymous hemianopsia and visual hallucinations.ConclusionsNeuro-ophthalmic manifestations of cholangiocarcinoma depend upon both mechanism and localization. We report five cases of cholangiocarcinoma with neuro-ophthalmologic findings. To our knowledge, this is the largest such series reported in the English language ophthalmic literature.

Original languageEnglish (US)
Pages (from-to)1245-1248
Number of pages4
JournalEye (Basingstoke)
Volume31
Issue number8
DOIs
StatePublished - Aug 1 2017

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Cholangiocarcinoma
Hemianopsia
Eye Manifestations
Abducens Nerve Diseases
Neoplasm Metastasis
Posterior Cranial Fossa
Occipital Lobe
Diplopia
Hallucinations
Tertiary Care Centers
Language
Stroke
Case Series
Manifestation
Muscles

ASJC Scopus subject areas

  • Ophthalmology
  • Arts and Humanities(all)

Cite this

Neuro-ophthalmologic manifestations of cholangiocarcinoma : A case series. / Rico, G.; Smith, S. V.; Siddiqui, Yusra; Whyte, A.; Gombos, D.; Lee, A. G.

In: Eye (Basingstoke), Vol. 31, No. 8, 01.08.2017, p. 1245-1248.

Research output: Contribution to journalArticle

Rico, G, Smith, SV, Siddiqui, Y, Whyte, A, Gombos, D & Lee, AG 2017, 'Neuro-ophthalmologic manifestations of cholangiocarcinoma: A case series', Eye (Basingstoke), vol. 31, no. 8, pp. 1245-1248. https://doi.org/10.1038/eye.2017.77
Rico, G. ; Smith, S. V. ; Siddiqui, Yusra ; Whyte, A. ; Gombos, D. ; Lee, A. G. / Neuro-ophthalmologic manifestations of cholangiocarcinoma : A case series. In: Eye (Basingstoke). 2017 ; Vol. 31, No. 8. pp. 1245-1248.
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