Neuronal lesions and behavioral modifications in rat following cerebral ischemia and reperfusion

G. Martinez, M. L. Carnazza, C. Di Giacomo, V. Sorrenti, R. Castana, G. Pennisi, J. R. Perez-Polo, A. Vanella

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Neurons of the mammalian CNS differ in their vulnerability to various disease processes and other insults, particularly in their response to total anoxia/ischemia. In this study we have tested the histological and behavioral modifications induced by experimental conditions of partial cerebral ischemia in the rats. The specific morphological and histological alterations, observed in our experimental conditions of reversible partial cerebral ischemia, confirm the selective vulnerability of certain neuronal populations to ischemic injury and are also evidenced by behavioral modifications which may mirror the functional impairment observed in humans after a transitory ischemic attack.

Original languageEnglish (US)
Pages (from-to)667-674
Number of pages8
JournalNeurochemical Research
Volume21
Issue number6
DOIs
StatePublished - Jun 1996
Externally publishedYes

Fingerprint

Brain Ischemia
Neurons
Reperfusion
Rats
Mirrors
Ischemia
Wounds and Injuries
Population
Hypoxia

Keywords

  • behavior
  • Cerebral ischemia
  • neuronal lesions
  • reperfusion

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry

Cite this

Martinez, G., Carnazza, M. L., Di Giacomo, C., Sorrenti, V., Castana, R., Pennisi, G., ... Vanella, A. (1996). Neuronal lesions and behavioral modifications in rat following cerebral ischemia and reperfusion. Neurochemical Research, 21(6), 667-674. https://doi.org/10.1007/BF02527723

Neuronal lesions and behavioral modifications in rat following cerebral ischemia and reperfusion. / Martinez, G.; Carnazza, M. L.; Di Giacomo, C.; Sorrenti, V.; Castana, R.; Pennisi, G.; Perez-Polo, J. R.; Vanella, A.

In: Neurochemical Research, Vol. 21, No. 6, 06.1996, p. 667-674.

Research output: Contribution to journalArticle

Martinez, G, Carnazza, ML, Di Giacomo, C, Sorrenti, V, Castana, R, Pennisi, G, Perez-Polo, JR & Vanella, A 1996, 'Neuronal lesions and behavioral modifications in rat following cerebral ischemia and reperfusion', Neurochemical Research, vol. 21, no. 6, pp. 667-674. https://doi.org/10.1007/BF02527723
Martinez G, Carnazza ML, Di Giacomo C, Sorrenti V, Castana R, Pennisi G et al. Neuronal lesions and behavioral modifications in rat following cerebral ischemia and reperfusion. Neurochemical Research. 1996 Jun;21(6):667-674. https://doi.org/10.1007/BF02527723
Martinez, G. ; Carnazza, M. L. ; Di Giacomo, C. ; Sorrenti, V. ; Castana, R. ; Pennisi, G. ; Perez-Polo, J. R. ; Vanella, A. / Neuronal lesions and behavioral modifications in rat following cerebral ischemia and reperfusion. In: Neurochemical Research. 1996 ; Vol. 21, No. 6. pp. 667-674.
@article{999ae2f88ec54d0ba0f8b28267f1f56e,
title = "Neuronal lesions and behavioral modifications in rat following cerebral ischemia and reperfusion",
abstract = "Neurons of the mammalian CNS differ in their vulnerability to various disease processes and other insults, particularly in their response to total anoxia/ischemia. In this study we have tested the histological and behavioral modifications induced by experimental conditions of partial cerebral ischemia in the rats. The specific morphological and histological alterations, observed in our experimental conditions of reversible partial cerebral ischemia, confirm the selective vulnerability of certain neuronal populations to ischemic injury and are also evidenced by behavioral modifications which may mirror the functional impairment observed in humans after a transitory ischemic attack.",
keywords = "behavior, Cerebral ischemia, neuronal lesions, reperfusion",
author = "G. Martinez and Carnazza, {M. L.} and {Di Giacomo}, C. and V. Sorrenti and R. Castana and G. Pennisi and Perez-Polo, {J. R.} and A. Vanella",
year = "1996",
month = "6",
doi = "10.1007/BF02527723",
language = "English (US)",
volume = "21",
pages = "667--674",
journal = "Neurochemical Research",
issn = "0364-3190",
publisher = "Springer New York",
number = "6",

}

TY - JOUR

T1 - Neuronal lesions and behavioral modifications in rat following cerebral ischemia and reperfusion

AU - Martinez, G.

AU - Carnazza, M. L.

AU - Di Giacomo, C.

AU - Sorrenti, V.

AU - Castana, R.

AU - Pennisi, G.

AU - Perez-Polo, J. R.

AU - Vanella, A.

PY - 1996/6

Y1 - 1996/6

N2 - Neurons of the mammalian CNS differ in their vulnerability to various disease processes and other insults, particularly in their response to total anoxia/ischemia. In this study we have tested the histological and behavioral modifications induced by experimental conditions of partial cerebral ischemia in the rats. The specific morphological and histological alterations, observed in our experimental conditions of reversible partial cerebral ischemia, confirm the selective vulnerability of certain neuronal populations to ischemic injury and are also evidenced by behavioral modifications which may mirror the functional impairment observed in humans after a transitory ischemic attack.

AB - Neurons of the mammalian CNS differ in their vulnerability to various disease processes and other insults, particularly in their response to total anoxia/ischemia. In this study we have tested the histological and behavioral modifications induced by experimental conditions of partial cerebral ischemia in the rats. The specific morphological and histological alterations, observed in our experimental conditions of reversible partial cerebral ischemia, confirm the selective vulnerability of certain neuronal populations to ischemic injury and are also evidenced by behavioral modifications which may mirror the functional impairment observed in humans after a transitory ischemic attack.

KW - behavior

KW - Cerebral ischemia

KW - neuronal lesions

KW - reperfusion

UR - http://www.scopus.com/inward/record.url?scp=0029995781&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029995781&partnerID=8YFLogxK

U2 - 10.1007/BF02527723

DO - 10.1007/BF02527723

M3 - Article

C2 - 8829138

AN - SCOPUS:0029995781

VL - 21

SP - 667

EP - 674

JO - Neurochemical Research

JF - Neurochemical Research

SN - 0364-3190

IS - 6

ER -