Abstract
Neurons of the mammalian CNS differ in their vulnerability to various disease processes and other insults, particularly in their response to total anoxia/ischemia. In this study we have tested the histological and behavioral modifications induced by experimental conditions of partial cerebral ischemia in the rats. The specific morphological and histological alterations, observed in our experimental conditions of reversible partial cerebral ischemia, confirm the selective vulnerability of certain neuronal populations to ischemic injury and are also evidenced by behavioral modifications which may mirror the functional impairment observed in humans after a transitory ischemic attack.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 667-674 |
| Number of pages | 8 |
| Journal | Neurochemical Research |
| Volume | 21 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 1996 |
| Externally published | Yes |
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Keywords
- behavior
- Cerebral ischemia
- neuronal lesions
- reperfusion
ASJC Scopus subject areas
- Neuroscience(all)
- Biochemistry
Cite this
Neuronal lesions and behavioral modifications in rat following cerebral ischemia and reperfusion. / Martinez, G.; Carnazza, M. L.; Di Giacomo, C.; Sorrenti, V.; Castana, R.; Pennisi, G.; Perez-Polo, J. R.; Vanella, A.
In: Neurochemical Research, Vol. 21, No. 6, 06.1996, p. 667-674.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Neuronal lesions and behavioral modifications in rat following cerebral ischemia and reperfusion
AU - Martinez, G.
AU - Carnazza, M. L.
AU - Di Giacomo, C.
AU - Sorrenti, V.
AU - Castana, R.
AU - Pennisi, G.
AU - Perez-Polo, J. R.
AU - Vanella, A.
PY - 1996/6
Y1 - 1996/6
N2 - Neurons of the mammalian CNS differ in their vulnerability to various disease processes and other insults, particularly in their response to total anoxia/ischemia. In this study we have tested the histological and behavioral modifications induced by experimental conditions of partial cerebral ischemia in the rats. The specific morphological and histological alterations, observed in our experimental conditions of reversible partial cerebral ischemia, confirm the selective vulnerability of certain neuronal populations to ischemic injury and are also evidenced by behavioral modifications which may mirror the functional impairment observed in humans after a transitory ischemic attack.
AB - Neurons of the mammalian CNS differ in their vulnerability to various disease processes and other insults, particularly in their response to total anoxia/ischemia. In this study we have tested the histological and behavioral modifications induced by experimental conditions of partial cerebral ischemia in the rats. The specific morphological and histological alterations, observed in our experimental conditions of reversible partial cerebral ischemia, confirm the selective vulnerability of certain neuronal populations to ischemic injury and are also evidenced by behavioral modifications which may mirror the functional impairment observed in humans after a transitory ischemic attack.
KW - behavior
KW - Cerebral ischemia
KW - neuronal lesions
KW - reperfusion
UR - http://www.scopus.com/inward/record.url?scp=0029995781&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029995781&partnerID=8YFLogxK
U2 - 10.1007/BF02527723
DO - 10.1007/BF02527723
M3 - Article
VL - 21
SP - 667
EP - 674
JO - Neurochemical Research
JF - Neurochemical Research
SN - 0364-3190
IS - 6
ER -