Neuropsychiatric effects of cocaine: Spect measurements

Bruce L. Miller; Ismael Mena; Robert Giombetti; Javier Villanueva-Meyer; A. H. Djenderedjian

doi:10.1300/J069v11n04_04

Neuropsychiatric effects of cocaine: Spect measurements

Bruce L. Miller, Ismael Mena, Robert Giombetti, Javier Villanueva-Meyer, A. H. Djenderedjian

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

Cocaine causes serious neurologic and neuropsychiatric complications. Cocaine-induced seizures are common and appear to be due to the local anaesthetic actions of this compound. Cocaine induced stroke has varied mechanisms. With ischemic stroke there is severe vasospasm induced by rises in brain catecholamines. These changes can persist for many weeks and can be demonstrated using single-photon emission computerized tomography (SPECT). In many patients with psychiatric symptoms induced by cocaine may be due to decreases in cerebral blood flow. In cocaine abuse, treatment strategies based on decreasing cerebral vasospasm need to be developed.

Original language	English (US)
Pages (from-to)	47-58
Number of pages	12
Journal	Journal of Addictive Diseases
Volume	11
Issue number	4
DOIs	https://doi.org/10.1300/J069v11n04_04
State	Published - Dec 9 1992
Externally published	Yes

ASJC Scopus subject areas

Medicine (miscellaneous)
Clinical Psychology
Psychiatry and Mental health

Access to Document

10.1300/J069v11n04_04

Cite this

@article{08d86f1711014fbb98518d417e82873f,

title = "Neuropsychiatric effects of cocaine: Spect measurements",

abstract = "Cocaine causes serious neurologic and neuropsychiatric complications. Cocaine-induced seizures are common and appear to be due to the local anaesthetic actions of this compound. Cocaine induced stroke has varied mechanisms. With ischemic stroke there is severe vasospasm induced by rises in brain catecholamines. These changes can persist for many weeks and can be demonstrated using single-photon emission computerized tomography (SPECT). In many patients with psychiatric symptoms induced by cocaine may be due to decreases in cerebral blood flow. In cocaine abuse, treatment strategies based on decreasing cerebral vasospasm need to be developed.",

author = "Miller, {Bruce L.} and Ismael Mena and Robert Giombetti and Javier Villanueva-Meyer and Djenderedjian, {A. H.}",

year = "1992",

month = dec,

day = "9",

doi = "10.1300/J069v11n04_04",

language = "English (US)",

volume = "11",

pages = "47--58",

journal = "Journal of Addictive Diseases",

issn = "1055-0887",

publisher = "Routledge",

number = "4",

}

TY - JOUR

T1 - Neuropsychiatric effects of cocaine

T2 - Spect measurements

AU - Miller, Bruce L.

AU - Mena, Ismael

AU - Giombetti, Robert

AU - Villanueva-Meyer, Javier

AU - Djenderedjian, A. H.

PY - 1992/12/9

Y1 - 1992/12/9

N2 - Cocaine causes serious neurologic and neuropsychiatric complications. Cocaine-induced seizures are common and appear to be due to the local anaesthetic actions of this compound. Cocaine induced stroke has varied mechanisms. With ischemic stroke there is severe vasospasm induced by rises in brain catecholamines. These changes can persist for many weeks and can be demonstrated using single-photon emission computerized tomography (SPECT). In many patients with psychiatric symptoms induced by cocaine may be due to decreases in cerebral blood flow. In cocaine abuse, treatment strategies based on decreasing cerebral vasospasm need to be developed.

AB - Cocaine causes serious neurologic and neuropsychiatric complications. Cocaine-induced seizures are common and appear to be due to the local anaesthetic actions of this compound. Cocaine induced stroke has varied mechanisms. With ischemic stroke there is severe vasospasm induced by rises in brain catecholamines. These changes can persist for many weeks and can be demonstrated using single-photon emission computerized tomography (SPECT). In many patients with psychiatric symptoms induced by cocaine may be due to decreases in cerebral blood flow. In cocaine abuse, treatment strategies based on decreasing cerebral vasospasm need to be developed.

UR - http://www.scopus.com/inward/record.url?scp=0027096426&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027096426&partnerID=8YFLogxK

U2 - 10.1300/J069v11n04_04

DO - 10.1300/J069v11n04_04

M3 - Article

C2 - 1486093

AN - SCOPUS:0027096426

SN - 1055-0887

VL - 11

SP - 47

EP - 58

JO - Journal of Addictive Diseases

JF - Journal of Addictive Diseases

IS - 4

ER -

Neuropsychiatric effects of cocaine: Spect measurements

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this