Neuropsychological outcome and quality of life following anterior craniofacial resection

Franco Demonte, David Callender, Christina Meyers, Paula Demasi

Research output: Contribution to journalArticle

Abstract

Few studies address the quality of life or the neuropsychological outcome of patients following treatment of skull base neoplasms. Difficulties arise because of the inhomogeneities inherent in the diverse patient and tumor populations encountered. Paranasal sinus tumors without brain invasion were chosen as the simplest tumor-patient paradigm. Nearly all of the patients maintained a high Karnofsky Performance Status and were independent. Neuropsychological test performance was average overall on tests of attention, psychomotor speed, recognition, and word fluency. Mild impairments of motor scanning speed (frontal/parietal), fine motor coordination/dexterity of the left hand, moderate impairments of executive function (prefrontal), and fine motor coordination/dexterity of the right hand were identified. QOL self-evaluations are highly subjective. Consequently, several patients who were highly functional and without medical or physical disability reported low QOL-probably anxiety-based. It should be noted that poor QOL based on neurologic or head and neck symptomatology was very infrequent. Anterior craniofacial resection and other indicated adjunctive therapies for paranasal sinus tumors do not adversely affect independence. Neuropsychological assessments do identify impairments in this patient population following treatment. The impairments noted were generally mild and very amendable to intervention. While 30% of the patients in this study reported an overall poor quality of life, this did not seem to be related to the presence of neurologic or head and neck symptoms.

Original languageEnglish (US)
Pages (from-to)45
Number of pages1
JournalSkull Base
Volume11
Issue numberSUPPL. 2
StatePublished - 2001
Externally publishedYes

Fingerprint

Quality of Life
Paranasal Sinuses
Nervous System
Skull Base Neoplasms
Neck
Hand
Head
Karnofsky Performance Status
Neoplasms
Diagnostic Self Evaluation
Neuropsychological Tests
Executive Function
Brain Neoplasms
Population
Therapeutics
Anxiety

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Demonte, F., Callender, D., Meyers, C., & Demasi, P. (2001). Neuropsychological outcome and quality of life following anterior craniofacial resection. Skull Base, 11(SUPPL. 2), 45.

Neuropsychological outcome and quality of life following anterior craniofacial resection. / Demonte, Franco; Callender, David; Meyers, Christina; Demasi, Paula.

In: Skull Base, Vol. 11, No. SUPPL. 2, 2001, p. 45.

Research output: Contribution to journalArticle

Demonte, F, Callender, D, Meyers, C & Demasi, P 2001, 'Neuropsychological outcome and quality of life following anterior craniofacial resection', Skull Base, vol. 11, no. SUPPL. 2, pp. 45.
Demonte F, Callender D, Meyers C, Demasi P. Neuropsychological outcome and quality of life following anterior craniofacial resection. Skull Base. 2001;11(SUPPL. 2):45.
Demonte, Franco ; Callender, David ; Meyers, Christina ; Demasi, Paula. / Neuropsychological outcome and quality of life following anterior craniofacial resection. In: Skull Base. 2001 ; Vol. 11, No. SUPPL. 2. pp. 45.
@article{b70641a181e14578be8f965d9cee482a,
title = "Neuropsychological outcome and quality of life following anterior craniofacial resection",
abstract = "Few studies address the quality of life or the neuropsychological outcome of patients following treatment of skull base neoplasms. Difficulties arise because of the inhomogeneities inherent in the diverse patient and tumor populations encountered. Paranasal sinus tumors without brain invasion were chosen as the simplest tumor-patient paradigm. Nearly all of the patients maintained a high Karnofsky Performance Status and were independent. Neuropsychological test performance was average overall on tests of attention, psychomotor speed, recognition, and word fluency. Mild impairments of motor scanning speed (frontal/parietal), fine motor coordination/dexterity of the left hand, moderate impairments of executive function (prefrontal), and fine motor coordination/dexterity of the right hand were identified. QOL self-evaluations are highly subjective. Consequently, several patients who were highly functional and without medical or physical disability reported low QOL-probably anxiety-based. It should be noted that poor QOL based on neurologic or head and neck symptomatology was very infrequent. Anterior craniofacial resection and other indicated adjunctive therapies for paranasal sinus tumors do not adversely affect independence. Neuropsychological assessments do identify impairments in this patient population following treatment. The impairments noted were generally mild and very amendable to intervention. While 30{\%} of the patients in this study reported an overall poor quality of life, this did not seem to be related to the presence of neurologic or head and neck symptoms.",
author = "Franco Demonte and David Callender and Christina Meyers and Paula Demasi",
year = "2001",
language = "English (US)",
volume = "11",
pages = "45",
journal = "Journal of Neurological Surgery, Part B: Skull Base",
issn = "2193-6331",
publisher = "Thieme Medical Publishers",
number = "SUPPL. 2",

}

TY - JOUR

T1 - Neuropsychological outcome and quality of life following anterior craniofacial resection

AU - Demonte, Franco

AU - Callender, David

AU - Meyers, Christina

AU - Demasi, Paula

PY - 2001

Y1 - 2001

N2 - Few studies address the quality of life or the neuropsychological outcome of patients following treatment of skull base neoplasms. Difficulties arise because of the inhomogeneities inherent in the diverse patient and tumor populations encountered. Paranasal sinus tumors without brain invasion were chosen as the simplest tumor-patient paradigm. Nearly all of the patients maintained a high Karnofsky Performance Status and were independent. Neuropsychological test performance was average overall on tests of attention, psychomotor speed, recognition, and word fluency. Mild impairments of motor scanning speed (frontal/parietal), fine motor coordination/dexterity of the left hand, moderate impairments of executive function (prefrontal), and fine motor coordination/dexterity of the right hand were identified. QOL self-evaluations are highly subjective. Consequently, several patients who were highly functional and without medical or physical disability reported low QOL-probably anxiety-based. It should be noted that poor QOL based on neurologic or head and neck symptomatology was very infrequent. Anterior craniofacial resection and other indicated adjunctive therapies for paranasal sinus tumors do not adversely affect independence. Neuropsychological assessments do identify impairments in this patient population following treatment. The impairments noted were generally mild and very amendable to intervention. While 30% of the patients in this study reported an overall poor quality of life, this did not seem to be related to the presence of neurologic or head and neck symptoms.

AB - Few studies address the quality of life or the neuropsychological outcome of patients following treatment of skull base neoplasms. Difficulties arise because of the inhomogeneities inherent in the diverse patient and tumor populations encountered. Paranasal sinus tumors without brain invasion were chosen as the simplest tumor-patient paradigm. Nearly all of the patients maintained a high Karnofsky Performance Status and were independent. Neuropsychological test performance was average overall on tests of attention, psychomotor speed, recognition, and word fluency. Mild impairments of motor scanning speed (frontal/parietal), fine motor coordination/dexterity of the left hand, moderate impairments of executive function (prefrontal), and fine motor coordination/dexterity of the right hand were identified. QOL self-evaluations are highly subjective. Consequently, several patients who were highly functional and without medical or physical disability reported low QOL-probably anxiety-based. It should be noted that poor QOL based on neurologic or head and neck symptomatology was very infrequent. Anterior craniofacial resection and other indicated adjunctive therapies for paranasal sinus tumors do not adversely affect independence. Neuropsychological assessments do identify impairments in this patient population following treatment. The impairments noted were generally mild and very amendable to intervention. While 30% of the patients in this study reported an overall poor quality of life, this did not seem to be related to the presence of neurologic or head and neck symptoms.

UR - http://www.scopus.com/inward/record.url?scp=33747765501&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33747765501&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:33747765501

VL - 11

SP - 45

JO - Journal of Neurological Surgery, Part B: Skull Base

JF - Journal of Neurological Surgery, Part B: Skull Base

SN - 2193-6331

IS - SUPPL. 2

ER -