Abstract
For decades, the interactions between the peripheral immune system and the brain have played a key role in disease. However, the molecular, biochemical, and cellular interactions that affect neuroimmune responses remain under investigation. Only in the last two decades has it become evident that the neuroimmune axis is reciprocal to maintaining health. When it becomes dysfunctional, it can underline disease pathobiology. This chapter focuses on what is known and what still remains to unravel the neuroimmune axis.
Original language | English (US) |
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Title of host publication | Neuroimmune Pharmacology and Therapeutics |
Subtitle of host publication | Third Edition |
Publisher | Springer Nature |
Pages | 233-247 |
Number of pages | 15 |
ISBN (Electronic) | 9783031682377 |
ISBN (Print) | 9783031682360 |
DOIs | |
State | Published - Jan 1 2024 |
Keywords
- Astrocytes
- Cell-to-cell communication
- Cytokines
- Dopamine
- Neurons
ASJC Scopus subject areas
- General Medicine
- General Immunology and Microbiology
- General Pharmacology, Toxicology and Pharmaceutics
- General Neuroscience