Neutralizing the Threat: Pan-Ebolavirus Antibodies Close the Loop

Research output: Contribution to journalShort surveypeer-review

6 Scopus citations

Abstract

The glycoprotein (GP) of ebolaviruses participates in a critical membrane fusion process to establish infection of a cell and therefore, represents an important target of both vaccines and antivirals. The latest reports on pan-ebolavirus monoclonal antibodies in small animal models may offer promising outcomes and insight into how best to target the GP in vaccine and antiviral discovery.

Original languageEnglish (US)
Pages (from-to)669-671
Number of pages3
JournalTrends in Molecular Medicine
Volume23
Issue number8
DOIs
StatePublished - Aug 2017

Keywords

  • Bundibugyo
  • Ebolavirus
  • Sudan
  • Zaire
  • antibody
  • treatment

ASJC Scopus subject areas

  • Molecular Medicine
  • Molecular Biology

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