New concepts in the diagnosis and management of neurocysticercosis (Taenia solium)

Hector H. Garcia, Oscar H. Del Brutto, Theodore E. Nash, A. Clinton White, Victor C W Tsang, Robert H. Gilman

Research output: Contribution to journalArticle

142 Scopus citations

Abstract

Human neurocysticercosis, the infection of the nervous system by the larvae of Taenia solium, is a major cause of epileptic seizures and other neurologic morbidity worldwide. The diagnosis and treatment of neurocysticercosis have been considerably improved in recent years. This improvement includes identification and sequencing of specific antigens and development of new assays for laboratory diagnosis, recognition of the frequency and significance of edema around old, calcified cysts (associated to symptomatic episodes), results of a randomized blinded control treatment trial on treatment efficacy for intraparenchymal disease showing a clinical benefit of decreased seizures, and a much better assessment of the frequency and spectrum of cerebrovascular complications. These advances now permit a much better integration of clinical, serologic, and imaging data for diagnosis and therapeutic purposes.

Original languageEnglish (US)
Pages (from-to)3-9
Number of pages7
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume72
Issue number1
StatePublished - Jan 2005
Externally publishedYes

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ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Garcia, H. H., Del Brutto, O. H., Nash, T. E., White, A. C., Tsang, V. C. W., & Gilman, R. H. (2005). New concepts in the diagnosis and management of neurocysticercosis (Taenia solium). American Journal of Tropical Medicine and Hygiene, 72(1), 3-9.