New evidence for the theory of chromosome organization by repetitive elements (CORE)

Shao Jun Tang

doi:10.3390/genes8020081

New evidence for the theory of chromosome organization by repetitive elements (CORE)

Shao Jun Tang

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Repetitive DNA elements were proposed to coordinate chromatin folding and interaction in chromosomes by their intrinsic homology-based clustering ability. A recent analysis of the data sets from chromosome-conformation-capture experiments confirms the spatial clustering of DNA repeats of the same family in the nuclear space, and thus provides strong new support for the CORE theory.

Original language	English (US)
Article number	81
Journal	Genes
Volume	8
Issue number	2
DOIs	https://doi.org/10.3390/genes8020081
State	Published - Feb 20 2017
Externally published	Yes

Keywords

CORE theory
Chromatin
Chromosome
Chromosome conformation capture
Repetitive DNA

ASJC Scopus subject areas

Genetics
Genetics(clinical)

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10.3390/genes8020081

Cite this

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title = "New evidence for the theory of chromosome organization by repetitive elements (CORE)",

abstract = "Repetitive DNA elements were proposed to coordinate chromatin folding and interaction in chromosomes by their intrinsic homology-based clustering ability. A recent analysis of the data sets from chromosome-conformation-capture experiments confirms the spatial clustering of DNA repeats of the same family in the nuclear space, and thus provides strong new support for the CORE theory.",

keywords = "CORE theory, Chromatin, Chromosome, Chromosome conformation capture, Repetitive DNA",

author = "Tang, {Shao Jun}",

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AB - Repetitive DNA elements were proposed to coordinate chromatin folding and interaction in chromosomes by their intrinsic homology-based clustering ability. A recent analysis of the data sets from chromosome-conformation-capture experiments confirms the spatial clustering of DNA repeats of the same family in the nuclear space, and thus provides strong new support for the CORE theory.

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KW - Chromatin

KW - Chromosome

KW - Chromosome conformation capture

KW - Repetitive DNA

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New evidence for the theory of chromosome organization by repetitive elements (CORE)

Abstract

Keywords

ASJC Scopus subject areas

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