New evidence for the theory of chromosome organization by repetitive elements (CORE)

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Abstract

Repetitive DNA elements were proposed to coordinate chromatin folding and interaction in chromosomes by their intrinsic homology-based clustering ability. A recent analysis of the data sets from chromosome-conformation-capture experiments confirms the spatial clustering of DNA repeats of the same family in the nuclear space, and thus provides strong new support for the CORE theory.

Original languageEnglish (US)
Article number81
JournalGenes
Volume8
Issue number2
DOIs
StatePublished - Feb 20 2017

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Keywords

  • Chromatin
  • Chromosome
  • Chromosome conformation capture
  • CORE theory
  • Repetitive DNA

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

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