Abstract
Repetitive DNA elements were proposed to coordinate chromatin folding and interaction in chromosomes by their intrinsic homology-based clustering ability. A recent analysis of the data sets from chromosome-conformation-capture experiments confirms the spatial clustering of DNA repeats of the same family in the nuclear space, and thus provides strong new support for the CORE theory.
| Original language | English (US) |
|---|---|
| Article number | 81 |
| Journal | Genes |
| Volume | 8 |
| Issue number | 2 |
| DOIs | |
| State | Published - Feb 20 2017 |
| Externally published | Yes |
Keywords
- CORE theory
- Chromatin
- Chromosome
- Chromosome conformation capture
- Repetitive DNA
ASJC Scopus subject areas
- Genetics
- Genetics(clinical)