New insights into molecular Ehrlichia chaffeensis-host interactions

Abdul Wakeel, Bing Zhu, Xue jie Yu, Jere W. McBride

Research output: Contribution to journalShort survey

22 Scopus citations

Abstract

Ehrlichia chaffeensis is an obligately intracellular bacterium that exhibits tropism for mononuclear phagocytes and survives by reprogramming the host cell. Here we review new information regarding the newly characterized effector molecules and the complex network of molecular host-pathogen interactions that the organism exploits enabling it to thrive and persist intracellularly.

Original languageEnglish (US)
Pages (from-to)337-345
Number of pages9
JournalMicrobes and Infection
Volume12
Issue number5
DOIs
StatePublished - May 1 2010

Keywords

  • Ankyrin proteins
  • Effector
  • Ehrlichia
  • Host-pathogen interaction
  • Tandem repeat proteins

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Infectious Diseases

Fingerprint Dive into the research topics of 'New insights into molecular Ehrlichia chaffeensis-host interactions'. Together they form a unique fingerprint.

  • Cite this