New insights into molecular Ehrlichia chaffeensis-host interactions

Abdul Wakeel, Bing Zhu, Xue jie Yu, Jere McBride

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Ehrlichia chaffeensis is an obligately intracellular bacterium that exhibits tropism for mononuclear phagocytes and survives by reprogramming the host cell. Here we review new information regarding the newly characterized effector molecules and the complex network of molecular host-pathogen interactions that the organism exploits enabling it to thrive and persist intracellularly.

Original languageEnglish (US)
Pages (from-to)337-345
Number of pages9
JournalMicrobes and Infection
Volume12
Issue number5
DOIs
StatePublished - May 2010

Fingerprint

Ehrlichia chaffeensis
Host-Pathogen Interactions
Tropism
Phagocytes
Bacteria
Cellular Reprogramming

Keywords

  • Ankyrin proteins
  • Effector
  • Ehrlichia
  • Host-pathogen interaction
  • Tandem repeat proteins

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Infectious Diseases

Cite this

New insights into molecular Ehrlichia chaffeensis-host interactions. / Wakeel, Abdul; Zhu, Bing; Yu, Xue jie; McBride, Jere.

In: Microbes and Infection, Vol. 12, No. 5, 05.2010, p. 337-345.

Research output: Contribution to journalArticle

Wakeel, Abdul ; Zhu, Bing ; Yu, Xue jie ; McBride, Jere. / New insights into molecular Ehrlichia chaffeensis-host interactions. In: Microbes and Infection. 2010 ; Vol. 12, No. 5. pp. 337-345.
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