New insights into molecular Ehrlichia chaffeensis-host interactions

Abdul Wakeel; Bing Zhu; Xue jie Yu; Jere W. McBride

doi:10.1016/j.micinf.2010.01.009

New insights into molecular Ehrlichia chaffeensis-host interactions

Abdul Wakeel, Bing Zhu, Xue jie Yu, Jere W. McBride

Pathology

Research output: Contribution to journal › Short survey › peer-review

28 Scopus citations

Abstract

Ehrlichia chaffeensis is an obligately intracellular bacterium that exhibits tropism for mononuclear phagocytes and survives by reprogramming the host cell. Here we review new information regarding the newly characterized effector molecules and the complex network of molecular host-pathogen interactions that the organism exploits enabling it to thrive and persist intracellularly.

Original language	English (US)
Pages (from-to)	337-345
Number of pages	9
Journal	Microbes and Infection
Volume	12
Issue number	5
DOIs	https://doi.org/10.1016/j.micinf.2010.01.009
State	Published - May 2010

Keywords

Ankyrin proteins
Effector
Ehrlichia
Host-pathogen interaction
Tandem repeat proteins

ASJC Scopus subject areas

Microbiology
Immunology
Infectious Diseases

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10.1016/j.micinf.2010.01.009

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title = "New insights into molecular Ehrlichia chaffeensis-host interactions",

abstract = "Ehrlichia chaffeensis is an obligately intracellular bacterium that exhibits tropism for mononuclear phagocytes and survives by reprogramming the host cell. Here we review new information regarding the newly characterized effector molecules and the complex network of molecular host-pathogen interactions that the organism exploits enabling it to thrive and persist intracellularly.",

keywords = "Ankyrin proteins, Effector, Ehrlichia, Host-pathogen interaction, Tandem repeat proteins",

author = "Abdul Wakeel and Bing Zhu and Yu, {Xue jie} and McBride, {Jere W.}",

note = "Funding Information: This work was supported by National Institute of Allergy and Infectious Diseases grant (AI 071145, AI 069270), and additional support was provided by the Clayton Foundation for Research.",

year = "2010",

month = may,

doi = "10.1016/j.micinf.2010.01.009",

language = "English (US)",

volume = "12",

pages = "337--345",

journal = "Microbes and Infection",

issn = "1286-4579",

publisher = "Elsevier Masson s.r.l.",

number = "5",

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TY - JOUR

T1 - New insights into molecular Ehrlichia chaffeensis-host interactions

AU - Wakeel, Abdul

AU - Zhu, Bing

AU - Yu, Xue jie

AU - McBride, Jere W.

N1 - Funding Information: This work was supported by National Institute of Allergy and Infectious Diseases grant (AI 071145, AI 069270), and additional support was provided by the Clayton Foundation for Research.

PY - 2010/5

Y1 - 2010/5

N2 - Ehrlichia chaffeensis is an obligately intracellular bacterium that exhibits tropism for mononuclear phagocytes and survives by reprogramming the host cell. Here we review new information regarding the newly characterized effector molecules and the complex network of molecular host-pathogen interactions that the organism exploits enabling it to thrive and persist intracellularly.

AB - Ehrlichia chaffeensis is an obligately intracellular bacterium that exhibits tropism for mononuclear phagocytes and survives by reprogramming the host cell. Here we review new information regarding the newly characterized effector molecules and the complex network of molecular host-pathogen interactions that the organism exploits enabling it to thrive and persist intracellularly.

KW - Ankyrin proteins

KW - Effector

KW - Ehrlichia

KW - Host-pathogen interaction

KW - Tandem repeat proteins

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UR - http://www.scopus.com/inward/citedby.url?scp=77950860206&partnerID=8YFLogxK

U2 - 10.1016/j.micinf.2010.01.009

DO - 10.1016/j.micinf.2010.01.009

M3 - Short survey

C2 - 20116446

AN - SCOPUS:77950860206

SN - 1286-4579

VL - 12

SP - 337

EP - 345

JO - Microbes and Infection

JF - Microbes and Infection

IS - 5

ER -

New insights into molecular Ehrlichia chaffeensis-host interactions

Abstract

Keywords

ASJC Scopus subject areas

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