New Insights into the Function of IAP Proteins: Modulation of the MYC/MAX/MAD Network

Casey Wright, Colin S. Duckett

Research output: Contribution to journalShort survey

3 Citations (Scopus)

Abstract

A growing number of studies have revealed that the inhibitor of apoptosis (IAP) proteins play a variety of cellular roles in addition to suppression of apoptosis. A recent study in Molecular Cell demonstrates that one IAP member, c-IAP1, functions to potentiate the activity of Myc by triggering the ubiquitination and proteasomal degradation of the Myc inhibitory protein Mad1.

Original languageEnglish (US)
Pages (from-to)3-4
Number of pages2
JournalDevelopmental Cell
Volume14
Issue number1
DOIs
StatePublished - Jan 15 2008
Externally publishedYes

Fingerprint

Inhibitor of Apoptosis Proteins
Modulation
Apoptosis
Ubiquitination
Degradation
Proteins
mycophenolic adenine dinucleotide

ASJC Scopus subject areas

  • Developmental Biology

Cite this

New Insights into the Function of IAP Proteins : Modulation of the MYC/MAX/MAD Network. / Wright, Casey; Duckett, Colin S.

In: Developmental Cell, Vol. 14, No. 1, 15.01.2008, p. 3-4.

Research output: Contribution to journalShort survey

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