New targets for antimalarial drug discovery

Francisco Guerra; Elizabeth A Winzeler

doi:10.1016/j.mib.2022.102220

New targets for antimalarial drug discovery

Francisco Guerra
, Elizabeth A Winzeler

Research output: Contribution to journal › Review article › peer-review

7 Scopus citations

Abstract

Phenotypic screening methods have placed numerous preclinical candidates into the antimalarial drug-discovery pipeline. As more chemically validated targets become available, efforts are shifting to target-based drug discovery. Here, we briefly review some of the most attractive targets that have been identified in recent years.

Original language	English (US)
Pages (from-to)	102220
Journal	Current Opinion in Microbiology
Volume	70
DOIs	https://doi.org/10.1016/j.mib.2022.102220
State	Published - Dec 2022
Externally published	Yes

Keywords

Antimalarials/pharmacology
Drug Discovery

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10.1016/j.mib.2022.102220

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@article{b2d4533c20184f7984a0e04cafcaa09c,

title = "New targets for antimalarial drug discovery",

abstract = "Phenotypic screening methods have placed numerous preclinical candidates into the antimalarial drug-discovery pipeline. As more chemically validated targets become available, efforts are shifting to target-based drug discovery. Here, we briefly review some of the most attractive targets that have been identified in recent years.",

keywords = "Antimalarials/pharmacology, Drug Discovery",

author = "Francisco Guerra and Winzeler, \{Elizabeth A\}",

note = "Copyright {\textcopyright} 2022. Published by Elsevier Ltd.",

year = "2022",

month = dec,

doi = "10.1016/j.mib.2022.102220",

language = "English (US)",

volume = "70",

pages = "102220",

journal = "Current Opinion in Microbiology",

issn = "1369-5274",

publisher = "Elsevier Ltd",

}

TY - JOUR

T1 - New targets for antimalarial drug discovery

AU - Guerra, Francisco

AU - Winzeler, Elizabeth A

PY - 2022/12

Y1 - 2022/12

N2 - Phenotypic screening methods have placed numerous preclinical candidates into the antimalarial drug-discovery pipeline. As more chemically validated targets become available, efforts are shifting to target-based drug discovery. Here, we briefly review some of the most attractive targets that have been identified in recent years.

AB - Phenotypic screening methods have placed numerous preclinical candidates into the antimalarial drug-discovery pipeline. As more chemically validated targets become available, efforts are shifting to target-based drug discovery. Here, we briefly review some of the most attractive targets that have been identified in recent years.

KW - Antimalarials/pharmacology

KW - Drug Discovery

U2 - 10.1016/j.mib.2022.102220

DO - 10.1016/j.mib.2022.102220

M3 - Review article

C2 - 36228458

SN - 1369-5274

VL - 70

SP - 102220

JO - Current Opinion in Microbiology

JF - Current Opinion in Microbiology

ER -

New targets for antimalarial drug discovery

Abstract

Keywords

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