New variants of glucose 6 phosphate dehydrogenase: G6PD Kilgore and G6PD Galveston

J. B. Alperin, G. C. Mills

Research output: Contribution to journalArticle

6 Scopus citations


Two new variants of glucose 6 phosphate dehydrogenase (G6PD) are described. G6PD Kilgore was discovered in an Ashkenazi Jewish man; G6PD Galveston was found in a Negro family. Both enzyme variants are associated with well compensated congenital nonspherocytic hemolytic disease. G6PD activity was measured in erythrocytes, leukocytes and platelets from individuals with G6PD Kilgore and G6PD Galveston. Enzyme preparations made from each of these cellular elements were utilized to determine biochemical and physical properties of each enzyme variant. The unique properties of G6PD Kilgore and G6PD Galveston are presented and compared with published properties of similar G6PD variants.

Original languageEnglish (US)
Pages (from-to)727-744
Number of pages18
JournalTexas reports on biology and medicine
Issue number4
StatePublished - Dec 1 1973


ASJC Scopus subject areas

  • Medicine(all)

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