Abstract
Two new variants of glucose 6 phosphate dehydrogenase (G6PD) are described. G6PD Kilgore was discovered in an Ashkenazi Jewish man; G6PD Galveston was found in a Negro family. Both enzyme variants are associated with well compensated congenital nonspherocytic hemolytic disease. G6PD activity was measured in erythrocytes, leukocytes and platelets from individuals with G6PD Kilgore and G6PD Galveston. Enzyme preparations made from each of these cellular elements were utilized to determine biochemical and physical properties of each enzyme variant. The unique properties of G6PD Kilgore and G6PD Galveston are presented and compared with published properties of similar G6PD variants.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 727-744 |
| Number of pages | 18 |
| Journal | Texas Reports on Biology and Medicine |
| Volume | 31 |
| Issue number | 4 |
| State | Published - 1973 |
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New variants of glucose 6 phosphate dehydrogenase : G6PD Kilgore and G6PD Galveston. / Alperin, J. B.; Mills, G. C.
In: Texas Reports on Biology and Medicine, Vol. 31, No. 4, 1973, p. 727-744.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - New variants of glucose 6 phosphate dehydrogenase
T2 - G6PD Kilgore and G6PD Galveston
AU - Alperin, J. B.
AU - Mills, G. C.
PY - 1973
Y1 - 1973
N2 - Two new variants of glucose 6 phosphate dehydrogenase (G6PD) are described. G6PD Kilgore was discovered in an Ashkenazi Jewish man; G6PD Galveston was found in a Negro family. Both enzyme variants are associated with well compensated congenital nonspherocytic hemolytic disease. G6PD activity was measured in erythrocytes, leukocytes and platelets from individuals with G6PD Kilgore and G6PD Galveston. Enzyme preparations made from each of these cellular elements were utilized to determine biochemical and physical properties of each enzyme variant. The unique properties of G6PD Kilgore and G6PD Galveston are presented and compared with published properties of similar G6PD variants.
AB - Two new variants of glucose 6 phosphate dehydrogenase (G6PD) are described. G6PD Kilgore was discovered in an Ashkenazi Jewish man; G6PD Galveston was found in a Negro family. Both enzyme variants are associated with well compensated congenital nonspherocytic hemolytic disease. G6PD activity was measured in erythrocytes, leukocytes and platelets from individuals with G6PD Kilgore and G6PD Galveston. Enzyme preparations made from each of these cellular elements were utilized to determine biochemical and physical properties of each enzyme variant. The unique properties of G6PD Kilgore and G6PD Galveston are presented and compared with published properties of similar G6PD variants.
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UR - http://www.scopus.com/inward/citedby.url?scp=0015714570&partnerID=8YFLogxK
M3 - Article
VL - 31
SP - 727
EP - 744
JO - Texas Reports on Biology and Medicine
JF - Texas Reports on Biology and Medicine
SN - 0040-4675
IS - 4
ER -