New variants of glucose 6 phosphate dehydrogenase

G6PD Kilgore and G6PD Galveston

J. B. Alperin, G. C. Mills

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Two new variants of glucose 6 phosphate dehydrogenase (G6PD) are described. G6PD Kilgore was discovered in an Ashkenazi Jewish man; G6PD Galveston was found in a Negro family. Both enzyme variants are associated with well compensated congenital nonspherocytic hemolytic disease. G6PD activity was measured in erythrocytes, leukocytes and platelets from individuals with G6PD Kilgore and G6PD Galveston. Enzyme preparations made from each of these cellular elements were utilized to determine biochemical and physical properties of each enzyme variant. The unique properties of G6PD Kilgore and G6PD Galveston are presented and compared with published properties of similar G6PD variants.

Original languageEnglish (US)
Pages (from-to)727-744
Number of pages18
JournalTexas Reports on Biology and Medicine
Volume31
Issue number4
StatePublished - 1973

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Glucosephosphate Dehydrogenase
Enzymes
Leukocytes
Blood Platelets
Erythrocytes

ASJC Scopus subject areas

  • Medicine(all)

Cite this

New variants of glucose 6 phosphate dehydrogenase : G6PD Kilgore and G6PD Galveston. / Alperin, J. B.; Mills, G. C.

In: Texas Reports on Biology and Medicine, Vol. 31, No. 4, 1973, p. 727-744.

Research output: Contribution to journalArticle

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