Nipah virus encephalitis reemergence, Bangladesh

Vincent P. Hsu, Mohammed Jahangir Hossain, Umesh D. Parashar, Mohammed Monsur Ali, Thomas Ksiazek, Ivan Kuzmin, Michael Niezgoda, Charles Rupprecht, Joseph Bresee, Robert F. Breiman

Research output: Contribution to journalArticle

351 Citations (Scopus)

Abstract

We retrospectively investigated two outbreaks of encephalitis in Meherpur and Naogaon, Bangladesh, which occurred in 2001 and 2003. We collected serum samples from persons who were ill, their household contacts, randomly selected residents, hospital workers, and various animals. Cases were classified as laboratory confirmed or probable. We identified 13 cases (4 confirmed, 9 probable) in Meherpur; 7 were in persons in two households. Patients were more likely than nonpatients to have close contact with other patients or have contact with a sick cow. In Naogaon, we identified 12 cases (4 confirmed, 8 probable); 7 were in persons clustered in 2 households. Two Pteropus bats had antibodies for Nipah virus. Samples from hospital workers were negative for Nipah virus antibodies. These outbreaks, the first since 1999, suggest that transmission may occur through close contact with other patients or from exposure to a common source. Surveillance and enhancement of diagnostic capacity to detect Nipah virus infection are recommended.

Original languageEnglish (US)
Pages (from-to)2082-2087
Number of pages6
JournalEmerging Infectious Diseases
Volume10
Issue number12
StatePublished - Dec 2004
Externally publishedYes

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Nipah Virus
Bangladesh
Encephalitis
Disease Outbreaks
Antibodies
Virus Diseases
Serum

ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

Hsu, V. P., Hossain, M. J., Parashar, U. D., Ali, M. M., Ksiazek, T., Kuzmin, I., ... Breiman, R. F. (2004). Nipah virus encephalitis reemergence, Bangladesh. Emerging Infectious Diseases, 10(12), 2082-2087.

Nipah virus encephalitis reemergence, Bangladesh. / Hsu, Vincent P.; Hossain, Mohammed Jahangir; Parashar, Umesh D.; Ali, Mohammed Monsur; Ksiazek, Thomas; Kuzmin, Ivan; Niezgoda, Michael; Rupprecht, Charles; Bresee, Joseph; Breiman, Robert F.

In: Emerging Infectious Diseases, Vol. 10, No. 12, 12.2004, p. 2082-2087.

Research output: Contribution to journalArticle

Hsu, VP, Hossain, MJ, Parashar, UD, Ali, MM, Ksiazek, T, Kuzmin, I, Niezgoda, M, Rupprecht, C, Bresee, J & Breiman, RF 2004, 'Nipah virus encephalitis reemergence, Bangladesh', Emerging Infectious Diseases, vol. 10, no. 12, pp. 2082-2087.
Hsu VP, Hossain MJ, Parashar UD, Ali MM, Ksiazek T, Kuzmin I et al. Nipah virus encephalitis reemergence, Bangladesh. Emerging Infectious Diseases. 2004 Dec;10(12):2082-2087.
Hsu, Vincent P. ; Hossain, Mohammed Jahangir ; Parashar, Umesh D. ; Ali, Mohammed Monsur ; Ksiazek, Thomas ; Kuzmin, Ivan ; Niezgoda, Michael ; Rupprecht, Charles ; Bresee, Joseph ; Breiman, Robert F. / Nipah virus encephalitis reemergence, Bangladesh. In: Emerging Infectious Diseases. 2004 ; Vol. 10, No. 12. pp. 2082-2087.
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