Nipah virus outbreak with person-to-person transmission in a district of Bangladesh, 2007

N. Homaira, M. Rahman, M. J. Hossain, J. H. Epstein, R. Sultana, M. S.U. Khan, G. Podder, K. Nahar, B. Ahmed, E. S. Gurley, P. Daszak, W. I. Lipkin, P. E. Rollin, J. A. Comer, T. G. Ksiazek, S. P. Luby

Research output: Contribution to journalArticle

94 Scopus citations

Abstract

In February 2007 an outbreak of Nipah virus (NiV) encephalitis in Thakurgaon District of northwest Bangladesh affected seven people, three of whom died. All subsequent cases developed illness 7-14 days after close physical contact with the index case while he was ill. Cases were more likely than controls to have been in the same room (100% vs. 95%, OR undefined, P<0001) and to have touched him (83% vs. 0%, OR undefined, P<0001). Although the source of infection for the index case was not identified, 50% of Pteropus bats sampled from near the outbreak area 1 month after the outbreak had antibodies to NiV confirming the presence of the virus in the area. The outbreak was spread by person-to-person transmission. Risk of NiV infection in family caregivers highlights the need for infection control practices to limit transmission of potentially infectious body secretions.

Original languageEnglish (US)
Pages (from-to)1630-1636
Number of pages7
JournalEpidemiology and infection
Volume138
Issue number11
DOIs
StatePublished - Nov 1 2010
Externally publishedYes

Keywords

  • Bangladesh
  • Nipah virus
  • person-to-person transmission

ASJC Scopus subject areas

  • Epidemiology
  • Infectious Diseases

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    Homaira, N., Rahman, M., Hossain, M. J., Epstein, J. H., Sultana, R., Khan, M. S. U., Podder, G., Nahar, K., Ahmed, B., Gurley, E. S., Daszak, P., Lipkin, W. I., Rollin, P. E., Comer, J. A., Ksiazek, T. G., & Luby, S. P. (2010). Nipah virus outbreak with person-to-person transmission in a district of Bangladesh, 2007. Epidemiology and infection, 138(11), 1630-1636. https://doi.org/10.1017/S0950268810000695