Nipah virus outbreak with person-to-person transmission in a district of Bangladesh, 2007

N. Homaira, M. Rahman, M. J. Hossain, J. H. Epstein, R. Sultana, M. S U Khan, G. Podder, K. Nahar, B. Ahmed, E. S. Gurley, P. Daszak, W. I. Lipkin, P. E. Rollin, J. A. Comer, Thomas Ksiazek, S. P. Luby

Research output: Contribution to journalArticle

90 Citations (Scopus)

Abstract

In February 2007 an outbreak of Nipah virus (NiV) encephalitis in Thakurgaon District of northwest Bangladesh affected seven people, three of whom died. All subsequent cases developed illness 7-14 days after close physical contact with the index case while he was ill. Cases were more likely than controls to have been in the same room (100% vs. 95%, OR undefined, P<0001) and to have touched him (83% vs. 0%, OR undefined, P<0001). Although the source of infection for the index case was not identified, 50% of Pteropus bats sampled from near the outbreak area 1 month after the outbreak had antibodies to NiV confirming the presence of the virus in the area. The outbreak was spread by person-to-person transmission. Risk of NiV infection in family caregivers highlights the need for infection control practices to limit transmission of potentially infectious body secretions.

Original languageEnglish (US)
Pages (from-to)1630-1636
Number of pages7
JournalEpidemiology and Infection
Volume138
Issue number11
DOIs
StatePublished - Nov 2010
Externally publishedYes

Fingerprint

Nipah Virus
Bangladesh
Disease Outbreaks
Virus Diseases
Encephalitis
Infection Control
Caregivers
Viruses
Antibodies
Infection

Keywords

  • Bangladesh
  • Nipah virus
  • person-to-person transmission

ASJC Scopus subject areas

  • Infectious Diseases
  • Epidemiology

Cite this

Homaira, N., Rahman, M., Hossain, M. J., Epstein, J. H., Sultana, R., Khan, M. S. U., ... Luby, S. P. (2010). Nipah virus outbreak with person-to-person transmission in a district of Bangladesh, 2007. Epidemiology and Infection, 138(11), 1630-1636. https://doi.org/10.1017/S0950268810000695

Nipah virus outbreak with person-to-person transmission in a district of Bangladesh, 2007. / Homaira, N.; Rahman, M.; Hossain, M. J.; Epstein, J. H.; Sultana, R.; Khan, M. S U; Podder, G.; Nahar, K.; Ahmed, B.; Gurley, E. S.; Daszak, P.; Lipkin, W. I.; Rollin, P. E.; Comer, J. A.; Ksiazek, Thomas; Luby, S. P.

In: Epidemiology and Infection, Vol. 138, No. 11, 11.2010, p. 1630-1636.

Research output: Contribution to journalArticle

Homaira, N, Rahman, M, Hossain, MJ, Epstein, JH, Sultana, R, Khan, MSU, Podder, G, Nahar, K, Ahmed, B, Gurley, ES, Daszak, P, Lipkin, WI, Rollin, PE, Comer, JA, Ksiazek, T & Luby, SP 2010, 'Nipah virus outbreak with person-to-person transmission in a district of Bangladesh, 2007', Epidemiology and Infection, vol. 138, no. 11, pp. 1630-1636. https://doi.org/10.1017/S0950268810000695
Homaira N, Rahman M, Hossain MJ, Epstein JH, Sultana R, Khan MSU et al. Nipah virus outbreak with person-to-person transmission in a district of Bangladesh, 2007. Epidemiology and Infection. 2010 Nov;138(11):1630-1636. https://doi.org/10.1017/S0950268810000695
Homaira, N. ; Rahman, M. ; Hossain, M. J. ; Epstein, J. H. ; Sultana, R. ; Khan, M. S U ; Podder, G. ; Nahar, K. ; Ahmed, B. ; Gurley, E. S. ; Daszak, P. ; Lipkin, W. I. ; Rollin, P. E. ; Comer, J. A. ; Ksiazek, Thomas ; Luby, S. P. / Nipah virus outbreak with person-to-person transmission in a district of Bangladesh, 2007. In: Epidemiology and Infection. 2010 ; Vol. 138, No. 11. pp. 1630-1636.
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