Nitazoxanide for treatment of intestinal parasites in children

Theresa J. Ochoa, A. Clinton White

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Nitazoxanide is an important new antiparasitic drug. It is effective for cryptosporidiosis in normal hosts, malnourished children and HIV patients with higher CD4 cell counts. Nitazoxanide is equivalent to metronidazole in giardiasis but may be better tolerated. It has wide spectrum activity against intestinal protozoan and helminth infections. Intestinal protozoa are important but underdiagnosed causes of persistent diarrhea in both developing and developed countries. Empiric therapy with nitazoxanide, which is effective, well-tolerated and modestly priced, may be a reasonable and more cost-effective alternative to pursuing specific diagnoses in selected populations.

Original languageEnglish (US)
Pages (from-to)641-642
Number of pages2
JournalPediatric Infectious Disease Journal
Volume24
Issue number7
DOIs
StatePublished - Jul 2005
Externally publishedYes

Fingerprint

nitazoxanide
Parasites
Protozoan Infections
Cryptosporidiosis
Giardiasis
Antiparasitic Agents
Helminths
Metronidazole
CD4 Lymphocyte Count
Developed Countries
Developing Countries
Diarrhea
Therapeutics
HIV
Costs and Cost Analysis
Population

Keywords

  • Diarrhea
  • Nitazoxanide
  • Parasites

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)

Cite this

Nitazoxanide for treatment of intestinal parasites in children. / Ochoa, Theresa J.; White, A. Clinton.

In: Pediatric Infectious Disease Journal, Vol. 24, No. 7, 07.2005, p. 641-642.

Research output: Contribution to journalArticle

@article{0664b5fa25c545de963b58db677388db,
title = "Nitazoxanide for treatment of intestinal parasites in children",
abstract = "Nitazoxanide is an important new antiparasitic drug. It is effective for cryptosporidiosis in normal hosts, malnourished children and HIV patients with higher CD4 cell counts. Nitazoxanide is equivalent to metronidazole in giardiasis but may be better tolerated. It has wide spectrum activity against intestinal protozoan and helminth infections. Intestinal protozoa are important but underdiagnosed causes of persistent diarrhea in both developing and developed countries. Empiric therapy with nitazoxanide, which is effective, well-tolerated and modestly priced, may be a reasonable and more cost-effective alternative to pursuing specific diagnoses in selected populations.",
keywords = "Diarrhea, Nitazoxanide, Parasites",
author = "Ochoa, {Theresa J.} and White, {A. Clinton}",
year = "2005",
month = "7",
doi = "10.1097/01.inf.0000171522.79099.c5",
language = "English (US)",
volume = "24",
pages = "641--642",
journal = "Pediatric Infectious Disease Journal",
issn = "0891-3668",
publisher = "Lippincott Williams and Wilkins",
number = "7",

}

TY - JOUR

T1 - Nitazoxanide for treatment of intestinal parasites in children

AU - Ochoa, Theresa J.

AU - White, A. Clinton

PY - 2005/7

Y1 - 2005/7

N2 - Nitazoxanide is an important new antiparasitic drug. It is effective for cryptosporidiosis in normal hosts, malnourished children and HIV patients with higher CD4 cell counts. Nitazoxanide is equivalent to metronidazole in giardiasis but may be better tolerated. It has wide spectrum activity against intestinal protozoan and helminth infections. Intestinal protozoa are important but underdiagnosed causes of persistent diarrhea in both developing and developed countries. Empiric therapy with nitazoxanide, which is effective, well-tolerated and modestly priced, may be a reasonable and more cost-effective alternative to pursuing specific diagnoses in selected populations.

AB - Nitazoxanide is an important new antiparasitic drug. It is effective for cryptosporidiosis in normal hosts, malnourished children and HIV patients with higher CD4 cell counts. Nitazoxanide is equivalent to metronidazole in giardiasis but may be better tolerated. It has wide spectrum activity against intestinal protozoan and helminth infections. Intestinal protozoa are important but underdiagnosed causes of persistent diarrhea in both developing and developed countries. Empiric therapy with nitazoxanide, which is effective, well-tolerated and modestly priced, may be a reasonable and more cost-effective alternative to pursuing specific diagnoses in selected populations.

KW - Diarrhea

KW - Nitazoxanide

KW - Parasites

UR - http://www.scopus.com/inward/record.url?scp=22244468741&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=22244468741&partnerID=8YFLogxK

U2 - 10.1097/01.inf.0000171522.79099.c5

DO - 10.1097/01.inf.0000171522.79099.c5

M3 - Article

VL - 24

SP - 641

EP - 642

JO - Pediatric Infectious Disease Journal

JF - Pediatric Infectious Disease Journal

SN - 0891-3668

IS - 7

ER -