Noncoupled Fluorescent Assay for Direct Real-Time Monitoring of Nicotinamide N-Methyltransferase Activity

Keyphrases

• Apoenzyme 22%
• Binary Complexes 22%
• Cardiovascular Disease 11%
• Chemical Library 11%
• Chronic Disease 11%
• Comparative Analysis 11%
• Competition Assay 11%
• Concentration-response Curve 11%
• Conformational Change 11%
• Detection Technology 11%
• Disease Conditions 11%
• Fluorescence Assay 100%
• Fluorescence Spectroscopy 11%
• High-throughput Screening 11%
• Initial Velocity 11%
• Intermolecular Interactions 11%
• Kidney Disease 11%
• Kinetic Data 11%
• Kinetic Parameters 11%
• Mechanism Parameters 11%
• Metabolic Disorders 11%
• Methionine 33%
• Methyl Groups 11%
• Methyltransferase Activity 100%
• Methyltransferase Inhibitor 33%
• Nicotinamide N-methyltransferase 100%
• Novel Assay 11%
• Osteoarthritis 11%
• Parkinson's Disease 11%
• Product Formation 11%
• Reaction Kinetics 11%
• Reaction Mechanism 33%
• Reaction Model 11%
• Reaction Products 11%
• Real-time Detection 11%
• Robust Detection 11%
• Small Molecules 11%
• Steady State 11%
• Substrate Competition 11%
• Substrate Concentration 11%
• Substrate-induced 11%
• Ternary Complex 11%
• Time Monitoring 100%
• Ultrasensitive 11%
• Velocity Information 11%

Biochemistry, Genetics and Molecular Biology

• Concentration Response 11%
• Conformational Change 11%
• Enzyme 11%
• Fluorescence Spectroscopy 11%
• High Throughput Screening 11%
• Kinetic Parameter 11%
• Methyltransferase 22%
• Nicotinamide N-Methyltransferase 100%
• S-Adenosyl Methionine 33%
• Small Molecule 11%
• Steady State 11%
• Substrate Concentration 11%
• Ternary Complex 11%