Nongrafted Skin Area Best Predicts Exercise Core Temperature Responses in Burned Humans

Matthew S. Ganio, Zachary J. Schlader, James Pearson, Rebekah A I Lucas, Daniel Gagnon, Eric Rivas, Karen J. Kowalske, Craig G. Crandall

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Grafted skin impairs heat dissipation, but it is unknown to what extent this affects body temperature during exercise in the heat. Purpose We examined core body temperature responses during exercise in the heat in a group of individuals with a large range of grafts covering their body surface area (BSA; 0%-75%). Methods Forty-three individuals (19 females) were stratified into groups based on BSA grafted: control (0% grafted, n = 9), 17%-40% (n = 19), and >40% (n = 15). Subjects exercised at a fixed rate of metabolic heat production (339 ± 70 W; 4.3 ± 0.8 W·kg-1) in an environmental chamber set at 40°C, 30% relative humidity for 90 min or until exhaustion (n = 8). Whole-body sweat rate and core temperatures were measured. Results Whole-body sweat rates were similar between the groups (control: 14.7 ± 3.4 mL·min-1, 17%-40%: 12.6 ± 4.0 mL·min-1; and >40%: 11.7 ± 4.4 mL·min-1; P > 0.05), but the increase in core temperature at the end of exercise in the >40% BSA grafted group (1.6°C ± 0.5°C) was greater than the 17%-40% (1.2°C ± 0.3°C) and control (0.9°C ± 0.2°C) groups (P < 0.05). Absolute BSA of nongrafted skin (expressed in square meters) was the strongest independent predictor of the core temperature increase (r2 = 0.41). When regrouping all subjects, individuals with the lowest BSA of nongrafted skin (<1.0 m2) had greater increases in core temperature (1.6°C ± 0.5°C) than those with more than 1.5 m2 nongrafted skin (1.0°C ± 0.3°C; P < 0.05). Conclusions These data imply that individuals with grafted skin have greater increases in core temperature when exercising in the heat and that the magnitude of this increase is best explained by the amount of nongrafted skin available for heat dissipation.

Original languageEnglish (US)
Pages (from-to)2224-2232
Number of pages9
JournalMedicine and Science in Sports and Exercise
Volume47
Issue number10
DOIs
StatePublished - Oct 19 2015
Externally publishedYes

Fingerprint

Hot Temperature
Skin
Temperature
Sweat
Body Temperature
Thermogenesis
Body Surface Area
Humidity
Transplants
Control Groups

Keywords

  • HEAT
  • SPLIT-THICKNESS GRAFT
  • THERMOREGULATION

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Ganio, M. S., Schlader, Z. J., Pearson, J., Lucas, R. A. I., Gagnon, D., Rivas, E., ... Crandall, C. G. (2015). Nongrafted Skin Area Best Predicts Exercise Core Temperature Responses in Burned Humans. Medicine and Science in Sports and Exercise, 47(10), 2224-2232. https://doi.org/10.1249/MSS.0000000000000655

Nongrafted Skin Area Best Predicts Exercise Core Temperature Responses in Burned Humans. / Ganio, Matthew S.; Schlader, Zachary J.; Pearson, James; Lucas, Rebekah A I; Gagnon, Daniel; Rivas, Eric; Kowalske, Karen J.; Crandall, Craig G.

In: Medicine and Science in Sports and Exercise, Vol. 47, No. 10, 19.10.2015, p. 2224-2232.

Research output: Contribution to journalArticle

Ganio, MS, Schlader, ZJ, Pearson, J, Lucas, RAI, Gagnon, D, Rivas, E, Kowalske, KJ & Crandall, CG 2015, 'Nongrafted Skin Area Best Predicts Exercise Core Temperature Responses in Burned Humans', Medicine and Science in Sports and Exercise, vol. 47, no. 10, pp. 2224-2232. https://doi.org/10.1249/MSS.0000000000000655
Ganio, Matthew S. ; Schlader, Zachary J. ; Pearson, James ; Lucas, Rebekah A I ; Gagnon, Daniel ; Rivas, Eric ; Kowalske, Karen J. ; Crandall, Craig G. / Nongrafted Skin Area Best Predicts Exercise Core Temperature Responses in Burned Humans. In: Medicine and Science in Sports and Exercise. 2015 ; Vol. 47, No. 10. pp. 2224-2232.
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abstract = "Grafted skin impairs heat dissipation, but it is unknown to what extent this affects body temperature during exercise in the heat. Purpose We examined core body temperature responses during exercise in the heat in a group of individuals with a large range of grafts covering their body surface area (BSA; 0{\%}-75{\%}). Methods Forty-three individuals (19 females) were stratified into groups based on BSA grafted: control (0{\%} grafted, n = 9), 17{\%}-40{\%} (n = 19), and >40{\%} (n = 15). Subjects exercised at a fixed rate of metabolic heat production (339 ± 70 W; 4.3 ± 0.8 W·kg-1) in an environmental chamber set at 40°C, 30{\%} relative humidity for 90 min or until exhaustion (n = 8). Whole-body sweat rate and core temperatures were measured. Results Whole-body sweat rates were similar between the groups (control: 14.7 ± 3.4 mL·min-1, 17{\%}-40{\%}: 12.6 ± 4.0 mL·min-1; and >40{\%}: 11.7 ± 4.4 mL·min-1; P > 0.05), but the increase in core temperature at the end of exercise in the >40{\%} BSA grafted group (1.6°C ± 0.5°C) was greater than the 17{\%}-40{\%} (1.2°C ± 0.3°C) and control (0.9°C ± 0.2°C) groups (P < 0.05). Absolute BSA of nongrafted skin (expressed in square meters) was the strongest independent predictor of the core temperature increase (r2 = 0.41). When regrouping all subjects, individuals with the lowest BSA of nongrafted skin (<1.0 m2) had greater increases in core temperature (1.6°C ± 0.5°C) than those with more than 1.5 m2 nongrafted skin (1.0°C ± 0.3°C; P < 0.05). Conclusions These data imply that individuals with grafted skin have greater increases in core temperature when exercising in the heat and that the magnitude of this increase is best explained by the amount of nongrafted skin available for heat dissipation.",
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AU - Rivas, Eric

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N2 - Grafted skin impairs heat dissipation, but it is unknown to what extent this affects body temperature during exercise in the heat. Purpose We examined core body temperature responses during exercise in the heat in a group of individuals with a large range of grafts covering their body surface area (BSA; 0%-75%). Methods Forty-three individuals (19 females) were stratified into groups based on BSA grafted: control (0% grafted, n = 9), 17%-40% (n = 19), and >40% (n = 15). Subjects exercised at a fixed rate of metabolic heat production (339 ± 70 W; 4.3 ± 0.8 W·kg-1) in an environmental chamber set at 40°C, 30% relative humidity for 90 min or until exhaustion (n = 8). Whole-body sweat rate and core temperatures were measured. Results Whole-body sweat rates were similar between the groups (control: 14.7 ± 3.4 mL·min-1, 17%-40%: 12.6 ± 4.0 mL·min-1; and >40%: 11.7 ± 4.4 mL·min-1; P > 0.05), but the increase in core temperature at the end of exercise in the >40% BSA grafted group (1.6°C ± 0.5°C) was greater than the 17%-40% (1.2°C ± 0.3°C) and control (0.9°C ± 0.2°C) groups (P < 0.05). Absolute BSA of nongrafted skin (expressed in square meters) was the strongest independent predictor of the core temperature increase (r2 = 0.41). When regrouping all subjects, individuals with the lowest BSA of nongrafted skin (<1.0 m2) had greater increases in core temperature (1.6°C ± 0.5°C) than those with more than 1.5 m2 nongrafted skin (1.0°C ± 0.3°C; P < 0.05). Conclusions These data imply that individuals with grafted skin have greater increases in core temperature when exercising in the heat and that the magnitude of this increase is best explained by the amount of nongrafted skin available for heat dissipation.

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