TY - JOUR
T1 - Noninvasive Raman spectroscopic identification of intraocular lens material in the living human eye
AU - Erckens, Roel J.
AU - March, Wayne F.
AU - Jongsma, Franciscus H.
AU - Wicksted, James P.
AU - Hendrikse, Frederick
AU - Smit, Eefke E.
AU - Motamedi, Massoud
PY - 2001
Y1 - 2001
N2 - Purpose: To develop a safe noninvasive technique for identifying the material of intraocular lenses (IOLs)implanted in patients. Setting: Center for Biomedical Engineering and the Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch, Galveston, Texas, USA. Methods: Raman spectroscopy was used to noninvasively identify the type of ICL implanted after previous cataract surgery in 9 eyes of 6 patients who were legally blind as a result of eye disease. Three IOLs were characterized: Poly(methyl methacrylate) (PMMA) (n = 5), acrylic (n = 3), and silicone (n = 1). Confocal Raman spectroscopy was used with a laser power of 95/μW and exposure time of 1 second. Results: Distinct spectral peaks associated with each type of ICL were obtained. These included spectra peaks at 2840 cm-1, 2946 cm-1, and 3000 cm-1 for PMMA; 2917 cm-1, 2939 cm-1, and 3055 cm-1 for acrylic; and 2900 cm-1, 2961 cm-1, and 3048 cm-1 for silicone. The procedure was well accepted by patients, and there were no complications. Conclusions' The specific Raman spectra of the IOLs allowed for noninvasive determination of ICL material with the use of a safe light dose and an exposure time of 1 second.
AB - Purpose: To develop a safe noninvasive technique for identifying the material of intraocular lenses (IOLs)implanted in patients. Setting: Center for Biomedical Engineering and the Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch, Galveston, Texas, USA. Methods: Raman spectroscopy was used to noninvasively identify the type of ICL implanted after previous cataract surgery in 9 eyes of 6 patients who were legally blind as a result of eye disease. Three IOLs were characterized: Poly(methyl methacrylate) (PMMA) (n = 5), acrylic (n = 3), and silicone (n = 1). Confocal Raman spectroscopy was used with a laser power of 95/μW and exposure time of 1 second. Results: Distinct spectral peaks associated with each type of ICL were obtained. These included spectra peaks at 2840 cm-1, 2946 cm-1, and 3000 cm-1 for PMMA; 2917 cm-1, 2939 cm-1, and 3055 cm-1 for acrylic; and 2900 cm-1, 2961 cm-1, and 3048 cm-1 for silicone. The procedure was well accepted by patients, and there were no complications. Conclusions' The specific Raman spectra of the IOLs allowed for noninvasive determination of ICL material with the use of a safe light dose and an exposure time of 1 second.
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U2 - 10.1016/S0886-3350(00)00828-2
DO - 10.1016/S0886-3350(00)00828-2
M3 - Article
C2 - 11489577
AN - SCOPUS:0034906690
SN - 0886-3350
VL - 27
SP - 1065
EP - 1070
JO - Journal of Cataract and Refractive Surgery
JF - Journal of Cataract and Refractive Surgery
IS - 7
ER -