Nonlinear optical behavior of ocular tissue during laser irradiation

Wei Chiang Lin; Massoud Motamedi; Ashley J. Welch

doi:10.1364/AO.34.007979

Nonlinear optical behavior of ocular tissue during laser irradiation

Wei Chiang Lin, Massoud Motamedi, Ashley J. Welch

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

A pump (cw Ho–YAG laser) and probe (He–Ne laser) system was used to study the dynamics of the optical behavior of ocular tissue during laser heating. The nonlinear optical behavior of porcine corneal and vitreous-humor tissue was characterized in vitro by means of measurements of the radial profile of a He–Ne laser beam transmitted through the tissue. Temperature gradients in the tissue created by the absorption of pump radiation caused the probe beam to diverge. For constant laser power, the rate of divergence was made dependent on the spot size of the pump beam. The profile of the transmitted probe beam returned to its original magnitude and shape after the tissue was permitted to cool. This reversible change in optical behavior was attributed to the formation of a negative lens owing to thermally induced local gradients in the refractive index of the tissue.

Original language	English (US)
Pages (from-to)	7979-7985
Number of pages	7
Journal	Applied Optics
Volume	34
Issue number	34
DOIs	https://doi.org/10.1364/AO.34.007979
State	Published - Dec 1995

Keywords

Nonlinear optics
Thermal lensing
Tissue optics

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics
Engineering (miscellaneous)
Electrical and Electronic Engineering

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10.1364/AO.34.007979

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title = "Nonlinear optical behavior of ocular tissue during laser irradiation",

abstract = "A pump (cw Ho–YAG laser) and probe (He–Ne laser) system was used to study the dynamics of the optical behavior of ocular tissue during laser heating. The nonlinear optical behavior of porcine corneal and vitreous-humor tissue was characterized in vitro by means of measurements of the radial profile of a He–Ne laser beam transmitted through the tissue. Temperature gradients in the tissue created by the absorption of pump radiation caused the probe beam to diverge. For constant laser power, the rate of divergence was made dependent on the spot size of the pump beam. The profile of the transmitted probe beam returned to its original magnitude and shape after the tissue was permitted to cool. This reversible change in optical behavior was attributed to the formation of a negative lens owing to thermally induced local gradients in the refractive index of the tissue.",

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AU - Motamedi, Massoud

AU - Welch, Ashley J.

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AB - A pump (cw Ho–YAG laser) and probe (He–Ne laser) system was used to study the dynamics of the optical behavior of ocular tissue during laser heating. The nonlinear optical behavior of porcine corneal and vitreous-humor tissue was characterized in vitro by means of measurements of the radial profile of a He–Ne laser beam transmitted through the tissue. Temperature gradients in the tissue created by the absorption of pump radiation caused the probe beam to diverge. For constant laser power, the rate of divergence was made dependent on the spot size of the pump beam. The profile of the transmitted probe beam returned to its original magnitude and shape after the tissue was permitted to cool. This reversible change in optical behavior was attributed to the formation of a negative lens owing to thermally induced local gradients in the refractive index of the tissue.

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KW - Thermal lensing

KW - Tissue optics

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Nonlinear optical behavior of ocular tissue during laser irradiation

Abstract

Keywords

ASJC Scopus subject areas

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