Nontunneled central venous catheters in patients with AIDS are associated with a low infection rate

Daniel J. Skiest, Patti Grant, Philip Keiser

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Patients with AIDS frequently require long-term central venous access devices for intravenous (IV) therapy. We reviewed the medical records of all HIV-infected patients at a single large urban hospital who had a central venous catheter (CVC) placed during a 1-year period to assess the overall complication rate, infection rate, and the microbiology of infectious complications. One hundred fifty-six catheters were inserted in 87 patients for 11,041 catheter days. These catheters (142 of 156) were primarily nontunneled, nonimplantable CVCs (NT-CVCs), and analyses were limited to these. Of these catheters, 79% were primarily used to treat disease caused by cytomegalovirus (CMV). The complication rate for the NT-CVCs was 5.1/1000 catheter days with a mean time to any complication of 106 days. The total infection rate of the NT-CVCs was 2.8/1000 catheter days, and the serious infection rate (bacteremia) for the NT-CVCs was 1.4/1000 catheter days. The mean time to a serious infection was 407 days. None of the following parameters was associated with an increased infection rate: HIV risk factor, indication for catheter, medications received via catheter, number of catheter ports, anatomic site of catheter insertion, or the presence of neutropenia. NT-CVCs were associated with low complication and infection rates that were comparable with historical rates seen in AIDS patients with tunneled and totally implantable central venous access devices. NT-CVCs may be a safe, cost-effective alternative to other central venous access devices in patients with HIV/AIDS.

Original languageEnglish (US)
Pages (from-to)220-226
Number of pages7
JournalJournal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Volume17
Issue number3
StatePublished - Mar 1 1998
Externally publishedYes

Fingerprint

Central Venous Catheters
Acquired Immunodeficiency Syndrome
Catheters
Infection
Equipment and Supplies
HIV
Vascular Access Devices
Urban Hospitals
Bacteremia
Microbiology
Neutropenia
Cytomegalovirus
HIV Infections
Medical Records
Costs and Cost Analysis

Keywords

  • AIDS
  • Catheter infection
  • Central venous catheter
  • HIV

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Virology

Cite this

Nontunneled central venous catheters in patients with AIDS are associated with a low infection rate. / Skiest, Daniel J.; Grant, Patti; Keiser, Philip.

In: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, Vol. 17, No. 3, 01.03.1998, p. 220-226.

Research output: Contribution to journalArticle

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