Whole-body bone scans remain the standard of care in the management of patients with suspected bone metastases. They are very sensitive for bone disease but are nonspecific. Various benign bone pathologies can give rise to foci of increased activity, which may mimic osteoblastic bone metastases. Whole-body PET with FDG has been shown to be of great value for the evaluation of bone metastases, with high sensitivity and specificity. This case shows normal FDG activity in a vertebra affected by Paget's disease and intense osteoblastic activity on the bone scan, a false-positive finding in the evaluation of suspected skeletal metastases.
- Bone scan
- FDG PET
- Paget's disease
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging