TY - JOUR
T1 - North American Solitaire Stent Retriever Acute Stroke registry
T2 - Post-marketing revascularization and clinical outcome results
AU - Zaidat, Osama O.
AU - Castonguay, Alicia C.
AU - Gupta, Rishi
AU - Sun, Chung Huan J.
AU - Martin, Coleman
AU - Holloway, William E.
AU - Mueller-Kronast, Nils
AU - English, Joey D.
AU - Linfante, Italo
AU - Dabus, Guilherme
AU - Malisch, Tim W.
AU - Marden, Franklin A.
AU - Bozorgchami, Hormozd
AU - Xavier, Andrew
AU - Rai, Ansaar T.
AU - Froehler, Michael T.
AU - Badruddin, Aamir
AU - Nguyen, Thanh N.
AU - Taqi, M. Asif
AU - Abraham, Michael G.
AU - Janardhan, Vallabh
AU - Shaltoni, Hashem
AU - Novakovic, Roberta
AU - Yoo, Albert J.
AU - Abou-Chebl, Alex
AU - Chen, Peng R.
AU - Britz, Gavin W.
AU - Kaushal, Ritesh
AU - Nanda, Ashish
AU - Issa, Mohammad A.
AU - Nogueira, Raul G.
PY - 2014/10/1
Y1 - 2014/10/1
N2 - Background Limited post-marketing data exist on the use of the Solitaire FR device in clinical practice. The North American Solitaire Stent Retriever Acute Stroke (NASA) registry aimed to assess the real world performance of the Solitaire FR device in contrast with the results from the SWIFT (Solitaire with the Intention for Thrombectomy) and TREVO 2 (Trevo versus Merci retrievers for thrombectomy revascularization of large vessel occlusions in acute ischemic stroke) trials. Methods The investigator initiated NASA registry recruited North American sites to submit retrospective angiographic and clinical outcome data on consecutive acute ischemic stroke (AIS) patients treated with the Solitaire FR between March 2012 and February 2013. The primary outcome was a Thrombolysis in Myocardial Ischemia (TIMI) score of ≥2 or a Treatment in Cerebral Infarction (TICI) score of ≥2a. Secondary outcomes were 90 day modified Rankin Scale (mRS) score, mortality, and symptomatic intracranial hemorrhage. Results 354 patients underwent treatment for AIS using the Solitaire FR device in 24 centers. Mean time from onset to groin puncture was 363.4±239 min, mean fluoroscopy time was 32.9±25.7 min, and mean procedure time was 100.9±57.8 min. Recanalization outcome: TIMI ≥2 rate of 83.3% (315/354) and TICI ≥2a rate of 87.5% (310/354) compared with the operator reported TIMI ≥2 rate of 83% in SWIFT and TICI ≥2a rate of 85% in TREVO 2. Clinical outcome: 42% (132/315) of NASA patients demonstrated a 90 day mRS ≤2 compared with 37% (SWIFT) and 40% (TREVO 2). 90 day mortality was 30≥2% (95/315) versus 17≥2% (SWIFT) and 29% (TREVO 2). Conclusions The NASA registry demonstrated that the Solitaire FR device performance in clinical practice is comparable with the SWIFT and TREVO 2 trial results.
AB - Background Limited post-marketing data exist on the use of the Solitaire FR device in clinical practice. The North American Solitaire Stent Retriever Acute Stroke (NASA) registry aimed to assess the real world performance of the Solitaire FR device in contrast with the results from the SWIFT (Solitaire with the Intention for Thrombectomy) and TREVO 2 (Trevo versus Merci retrievers for thrombectomy revascularization of large vessel occlusions in acute ischemic stroke) trials. Methods The investigator initiated NASA registry recruited North American sites to submit retrospective angiographic and clinical outcome data on consecutive acute ischemic stroke (AIS) patients treated with the Solitaire FR between March 2012 and February 2013. The primary outcome was a Thrombolysis in Myocardial Ischemia (TIMI) score of ≥2 or a Treatment in Cerebral Infarction (TICI) score of ≥2a. Secondary outcomes were 90 day modified Rankin Scale (mRS) score, mortality, and symptomatic intracranial hemorrhage. Results 354 patients underwent treatment for AIS using the Solitaire FR device in 24 centers. Mean time from onset to groin puncture was 363.4±239 min, mean fluoroscopy time was 32.9±25.7 min, and mean procedure time was 100.9±57.8 min. Recanalization outcome: TIMI ≥2 rate of 83.3% (315/354) and TICI ≥2a rate of 87.5% (310/354) compared with the operator reported TIMI ≥2 rate of 83% in SWIFT and TICI ≥2a rate of 85% in TREVO 2. Clinical outcome: 42% (132/315) of NASA patients demonstrated a 90 day mRS ≤2 compared with 37% (SWIFT) and 40% (TREVO 2). 90 day mortality was 30≥2% (95/315) versus 17≥2% (SWIFT) and 29% (TREVO 2). Conclusions The NASA registry demonstrated that the Solitaire FR device performance in clinical practice is comparable with the SWIFT and TREVO 2 trial results.
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U2 - 10.1136/neurintsurg-2013-010895
DO - 10.1136/neurintsurg-2013-010895
M3 - Article
C2 - 24062252
AN - SCOPUS:84907004072
SN - 1759-8478
VL - 6
SP - 584
EP - 588
JO - Journal of neurointerventional surgery
JF - Journal of neurointerventional surgery
IS - 8
ER -