Not So EASE-Y: How Often do Hospitalized Infective Endocarditis Patients Meet Criteria for Early Surgery?

Mohammad Amin Kashef, Auras R. Atreya, Jaime Hernandez-Montfort, Jennifer Frideric, Tara Lagu

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Infective endocarditis (IE) has historically caused significant morbidity and mortality. Valve surgery reduces systemic embolization and mortality, but the optimal timing is controversial. The EASE (Early Surgery Versus Conventional Treatment for Infective Endocarditis) trial, which employed strict inclusion and exclusion criteria, showed that early surgery could reduce the risk of embolic events for a subset of patients. The aim of the present study was to determine the proportion of adult IE patients seen in usual clinical practice at a single tertiary medical center that would meet EASE enrollment criteria. Over a four-year period, only 10 of 88 patients (11.3%) were found to meet EASE enrollment criteria. These results have important research implications, and highlight the differences between populations of patients used in clinical trials and patients seen in practice.

Original languageEnglish (US)
Pages (from-to)72-74
Number of pages3
JournalThe Journal of heart valve disease
Volume25
Issue number1
StatePublished - Jan 1 2016
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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    Amin Kashef, M., Atreya, A. R., Hernandez-Montfort, J., Frideric, J., & Lagu, T. (2016). Not So EASE-Y: How Often do Hospitalized Infective Endocarditis Patients Meet Criteria for Early Surgery? The Journal of heart valve disease, 25(1), 72-74.