Novel finding of optic nerve central T2 hypointensity utilizing 3 tesla MR imaging

Roy Riascos, John Heymann, Reza Hakimelahi, Khader Hasan, Ashot Sargsyan, Yael R. Barr, James Tom, Noam Alperin, Larry A. Kramer

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

We sought to report a central T2 hypointensity within the optic nerve on 3 T MRI studies obtained as part of the NASA Flight Medicine Visual Impairment Intracranial Pressure Protocol that had not been described previously. Twenty-one astronauts, who had undergone MRI of both orbits with direct coronal T2 sequences between 2010 and 2012, were retrospectively included. Two of the astronauts did not have previous exposure to microgravity at the time of their scans. A central T2 hypointensity was observed in 100% of both right and left eyes. It was completely visualized throughout the nerve course in 15 right eyes (71.4%) and in 19 left eyes (90.5%).We describe a new finding seen in all study participants: a central T2 hypointensity in the epicenter of the optic nerve. We speculate that this T2 hypointensity may represent flow voids caused by the central retinal vessels.

Original languageEnglish (US)
Pages (from-to)133-136
Number of pages4
JournalNeuroradiology Journal
Volume28
Issue number2
DOIs
StatePublished - Apr 1 2015

Fingerprint

Optic Nerve
Astronauts
United States National Aeronautics and Space Administration
Weightlessness
Retinal Vessels
Vision Disorders
Intracranial Pressure
Orbit
Medicine

Keywords

  • 3 Tesla
  • MR imaging
  • Optic nerve
  • T2 hypointensity

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging

Cite this

Riascos, R., Heymann, J., Hakimelahi, R., Hasan, K., Sargsyan, A., Barr, Y. R., ... Kramer, L. A. (2015). Novel finding of optic nerve central T2 hypointensity utilizing 3 tesla MR imaging. Neuroradiology Journal, 28(2), 133-136. https://doi.org/10.1177/1971400915576668

Novel finding of optic nerve central T2 hypointensity utilizing 3 tesla MR imaging. / Riascos, Roy; Heymann, John; Hakimelahi, Reza; Hasan, Khader; Sargsyan, Ashot; Barr, Yael R.; Tom, James; Alperin, Noam; Kramer, Larry A.

In: Neuroradiology Journal, Vol. 28, No. 2, 01.04.2015, p. 133-136.

Research output: Contribution to journalArticle

Riascos, R, Heymann, J, Hakimelahi, R, Hasan, K, Sargsyan, A, Barr, YR, Tom, J, Alperin, N & Kramer, LA 2015, 'Novel finding of optic nerve central T2 hypointensity utilizing 3 tesla MR imaging', Neuroradiology Journal, vol. 28, no. 2, pp. 133-136. https://doi.org/10.1177/1971400915576668
Riascos, Roy ; Heymann, John ; Hakimelahi, Reza ; Hasan, Khader ; Sargsyan, Ashot ; Barr, Yael R. ; Tom, James ; Alperin, Noam ; Kramer, Larry A. / Novel finding of optic nerve central T2 hypointensity utilizing 3 tesla MR imaging. In: Neuroradiology Journal. 2015 ; Vol. 28, No. 2. pp. 133-136.
@article{b20d0608223443959be2ab46cce86bcf,
title = "Novel finding of optic nerve central T2 hypointensity utilizing 3 tesla MR imaging",
abstract = "We sought to report a central T2 hypointensity within the optic nerve on 3 T MRI studies obtained as part of the NASA Flight Medicine Visual Impairment Intracranial Pressure Protocol that had not been described previously. Twenty-one astronauts, who had undergone MRI of both orbits with direct coronal T2 sequences between 2010 and 2012, were retrospectively included. Two of the astronauts did not have previous exposure to microgravity at the time of their scans. A central T2 hypointensity was observed in 100{\%} of both right and left eyes. It was completely visualized throughout the nerve course in 15 right eyes (71.4{\%}) and in 19 left eyes (90.5{\%}).We describe a new finding seen in all study participants: a central T2 hypointensity in the epicenter of the optic nerve. We speculate that this T2 hypointensity may represent flow voids caused by the central retinal vessels.",
keywords = "3 Tesla, MR imaging, Optic nerve, T2 hypointensity",
author = "Roy Riascos and John Heymann and Reza Hakimelahi and Khader Hasan and Ashot Sargsyan and Barr, {Yael R.} and James Tom and Noam Alperin and Kramer, {Larry A.}",
year = "2015",
month = "4",
day = "1",
doi = "10.1177/1971400915576668",
language = "English (US)",
volume = "28",
pages = "133--136",
journal = "Neuroradiology Journal",
issn = "1971-4009",
publisher = "Centauro srl",
number = "2",

}

TY - JOUR

T1 - Novel finding of optic nerve central T2 hypointensity utilizing 3 tesla MR imaging

AU - Riascos, Roy

AU - Heymann, John

AU - Hakimelahi, Reza

AU - Hasan, Khader

AU - Sargsyan, Ashot

AU - Barr, Yael R.

AU - Tom, James

AU - Alperin, Noam

AU - Kramer, Larry A.

PY - 2015/4/1

Y1 - 2015/4/1

N2 - We sought to report a central T2 hypointensity within the optic nerve on 3 T MRI studies obtained as part of the NASA Flight Medicine Visual Impairment Intracranial Pressure Protocol that had not been described previously. Twenty-one astronauts, who had undergone MRI of both orbits with direct coronal T2 sequences between 2010 and 2012, were retrospectively included. Two of the astronauts did not have previous exposure to microgravity at the time of their scans. A central T2 hypointensity was observed in 100% of both right and left eyes. It was completely visualized throughout the nerve course in 15 right eyes (71.4%) and in 19 left eyes (90.5%).We describe a new finding seen in all study participants: a central T2 hypointensity in the epicenter of the optic nerve. We speculate that this T2 hypointensity may represent flow voids caused by the central retinal vessels.

AB - We sought to report a central T2 hypointensity within the optic nerve on 3 T MRI studies obtained as part of the NASA Flight Medicine Visual Impairment Intracranial Pressure Protocol that had not been described previously. Twenty-one astronauts, who had undergone MRI of both orbits with direct coronal T2 sequences between 2010 and 2012, were retrospectively included. Two of the astronauts did not have previous exposure to microgravity at the time of their scans. A central T2 hypointensity was observed in 100% of both right and left eyes. It was completely visualized throughout the nerve course in 15 right eyes (71.4%) and in 19 left eyes (90.5%).We describe a new finding seen in all study participants: a central T2 hypointensity in the epicenter of the optic nerve. We speculate that this T2 hypointensity may represent flow voids caused by the central retinal vessels.

KW - 3 Tesla

KW - MR imaging

KW - Optic nerve

KW - T2 hypointensity

UR - http://www.scopus.com/inward/record.url?scp=84962016045&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84962016045&partnerID=8YFLogxK

U2 - 10.1177/1971400915576668

DO - 10.1177/1971400915576668

M3 - Article

C2 - 25923682

AN - SCOPUS:84962016045

VL - 28

SP - 133

EP - 136

JO - Neuroradiology Journal

JF - Neuroradiology Journal

SN - 1971-4009

IS - 2

ER -