@inproceedings{e97486ec6fe047fdab766f31740d5a0b,
title = "Novel focused optoacoustic transducers for accurate monitoring of total hemoglobin concentration and oxyhemoglobin saturation: Pre-clinical and clinical tests",
abstract = "We developed an optoacoustic technique for noninvasive, accurate, and continuous monitoring of total hemoglobin concentration and venous oxyhemoglobin saturation by probing specific blood vessels. In this work we report the development and tests of novel, focused optoacoustic transducers that provide blood vessel probing with sub-millimeter lateral resolution. The focused transducers were incorporated in our highly portable, laser diode-based optoacoustic monitoring system for pre-clinical and clinical tests. Our studies demonstrated that: 1) the focused transducer response is linearly dependent on blood total hemoglobin concentration with a high correlation coefficient; and 2) the sub-millimeter lateral resolution provided higher specificity of blood vessel probing, in particular, for smaller blood vessels such as the radial artery (diameter 2-3 mm).",
keywords = "Focused transducer, Noninvasive monitoring, Optoacoustics, Total hemoglobin concentration",
author = "Emanuel S{\"a}rchen and Irina Petrova and Yuriy Petrov and Donald Prough and Walter Neu and Esenaliev, {Rinat O.}",
year = "2010",
doi = "10.1117/12.847084",
language = "English (US)",
isbn = "9780819479600",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Photons Plus Ultrasound",
note = "Photons Plus Ultrasound: Imaging and Sensing 2010 ; Conference date: 24-01-2010 Through 26-01-2010",
}