Novel small molecule inhibitors of PTP1B

Biochemistry, Genetics and Molecular Biology

• Enzyme 50%
• Insulin 50%
• Insulin Receptor 100%
• Insulin Sensitivity 50%
• Leptin 50%
• Maturity Onset Diabetes of the Young 50%
• Protein Tyrosine Phosphatase 50%
• Receptor Tyrosine Kinase 50%
• Signal Transduction 50%
• Small Molecule 100%
• Tyrosine 100%

Pharmacology, Toxicology and Pharmaceutical Science

• Diseases 50%
• Enzymes 50%
• Insulin 100%
• Insulin Receptor 100%
• Leptin 50%
• Maturity Onset Diabetes of the Young 50%
• Protein Tyrosine Kinase 50%
• Protein Tyrosine Phosphatase 50%
• Receptor 50%
• Tyrosine 100%

Keyphrases

• Assay Method 20%
• Dephosphorylate 20%
• Induced Resistance 20%
• Insulin 20%
• Insulin Receptor 20%
• Insulin Receptor Kinase 20%
• Insulin Sensitivity 20%
• Leptin 20%
• Negative Regulator 20%
• Obesity 20%
• Protein Tyrosine Phosphatase 1B (PTP1B) 100%
• PTP1B Inhibitors 40%
• Receptor Tyrosine Kinase 20%
• Resistance to Insulin 20%
• Signaling Pathway 20%
• Small Molecule Inhibitors 100%
• Small Molecules 20%
• Therapeutic Target 20%
• Type 2 Diabetes Mellitus (T2DM) 20%
• Tyrosine Kinase Domain 20%
• Tyrosine Residue 20%
• World Population 20%