TY - JOUR
T1 - Novel technologies to enhance solubility of food-derived bioactive compounds
T2 - A review
AU - Recharla, Neeraja
AU - Riaz, Muhammad
AU - Ko, Sanghoon
AU - Park, Sungkwon
N1 - Funding Information:
This work was carried out with the support of “ Cooperative Research Program for Agriculture Science & Technology Development (Project No. PJ012615 )” Rural Development Administration, South Korea.
Publisher Copyright:
© 2017 Elsevier Ltd
PY - 2017/12
Y1 - 2017/12
N2 - Food-derived multifunctional bioactive compounds, such as carotenoids, fat soluble vitamins, phytosterols, polyunsaturated lipids, curcuminoids and flavonoid compounds provide promising therapeutic health benefits. However, the efforts in identifying their mode of action and applying them into food industry are still unsuccessful because majority of these compounds are water-insoluble and ingested are not delivered to the site of action, therefore, less bioavailable. Several strategies to enhance the water solubility have been developed over the years. There has been active research in the area during recent times. The present review will comprehensively discuss about novel technologies which have used to improve the aqueous solubility of bioactives.
AB - Food-derived multifunctional bioactive compounds, such as carotenoids, fat soluble vitamins, phytosterols, polyunsaturated lipids, curcuminoids and flavonoid compounds provide promising therapeutic health benefits. However, the efforts in identifying their mode of action and applying them into food industry are still unsuccessful because majority of these compounds are water-insoluble and ingested are not delivered to the site of action, therefore, less bioavailable. Several strategies to enhance the water solubility have been developed over the years. There has been active research in the area during recent times. The present review will comprehensively discuss about novel technologies which have used to improve the aqueous solubility of bioactives.
KW - Emulsification
KW - Inclusion complexation
KW - Natural bioactive compounds
KW - Solubility
KW - Supercritical fluids
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U2 - 10.1016/j.jff.2017.10.001
DO - 10.1016/j.jff.2017.10.001
M3 - Review article
AN - SCOPUS:85032859295
SN - 1756-4646
VL - 39
SP - 63
EP - 73
JO - Journal of Functional Foods
JF - Journal of Functional Foods
ER -