Numbers of rat dorsal root axons and ganglion cells during postnatal development.

C. E. Hulsebosch, R. E. Coggeshall, K. Chung

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

The present study demonstrates that T4 and S2 rat dorsal root axons decrease significantly from birth to adulthood with almost all of the decrease occurring in the first two weeks of life. Dorsal root ganglion cell numbers do not change during this time period. This is thus an example of postnatal axon elimination not associated with death of the cells that give rise to the axons. Presumably this regressive process is important in the formation of the normal adult nervous system. In addition, these findings raise the possibility that certain types of neonatal denervation may increase adult axon numbers by stopping a regressive process, the loss of axons, rather than initiating a progressive process, the formation of new axons.

Original languageEnglish (US)
Pages (from-to)105-113
Number of pages9
JournalBrain Research
Volume391
Issue number1
StatePublished - Apr 1986
Externally publishedYes

Fingerprint

Spinal Ganglia
Axons
Spinal Nerve Roots
Denervation
Nervous System
Cell Death
Cell Count
Parturition

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Hulsebosch, C. E., Coggeshall, R. E., & Chung, K. (1986). Numbers of rat dorsal root axons and ganglion cells during postnatal development. Brain Research, 391(1), 105-113.

Numbers of rat dorsal root axons and ganglion cells during postnatal development. / Hulsebosch, C. E.; Coggeshall, R. E.; Chung, K.

In: Brain Research, Vol. 391, No. 1, 04.1986, p. 105-113.

Research output: Contribution to journalArticle

Hulsebosch, CE, Coggeshall, RE & Chung, K 1986, 'Numbers of rat dorsal root axons and ganglion cells during postnatal development.', Brain Research, vol. 391, no. 1, pp. 105-113.
Hulsebosch CE, Coggeshall RE, Chung K. Numbers of rat dorsal root axons and ganglion cells during postnatal development. Brain Research. 1986 Apr;391(1):105-113.
Hulsebosch, C. E. ; Coggeshall, R. E. ; Chung, K. / Numbers of rat dorsal root axons and ganglion cells during postnatal development. In: Brain Research. 1986 ; Vol. 391, No. 1. pp. 105-113.
@article{9ddb53f191684787a828230a771ee589,
title = "Numbers of rat dorsal root axons and ganglion cells during postnatal development.",
abstract = "The present study demonstrates that T4 and S2 rat dorsal root axons decrease significantly from birth to adulthood with almost all of the decrease occurring in the first two weeks of life. Dorsal root ganglion cell numbers do not change during this time period. This is thus an example of postnatal axon elimination not associated with death of the cells that give rise to the axons. Presumably this regressive process is important in the formation of the normal adult nervous system. In addition, these findings raise the possibility that certain types of neonatal denervation may increase adult axon numbers by stopping a regressive process, the loss of axons, rather than initiating a progressive process, the formation of new axons.",
author = "Hulsebosch, {C. E.} and Coggeshall, {R. E.} and K. Chung",
year = "1986",
month = "4",
language = "English (US)",
volume = "391",
pages = "105--113",
journal = "Brain Research",
issn = "0006-8993",
publisher = "Elsevier",
number = "1",

}

TY - JOUR

T1 - Numbers of rat dorsal root axons and ganglion cells during postnatal development.

AU - Hulsebosch, C. E.

AU - Coggeshall, R. E.

AU - Chung, K.

PY - 1986/4

Y1 - 1986/4

N2 - The present study demonstrates that T4 and S2 rat dorsal root axons decrease significantly from birth to adulthood with almost all of the decrease occurring in the first two weeks of life. Dorsal root ganglion cell numbers do not change during this time period. This is thus an example of postnatal axon elimination not associated with death of the cells that give rise to the axons. Presumably this regressive process is important in the formation of the normal adult nervous system. In addition, these findings raise the possibility that certain types of neonatal denervation may increase adult axon numbers by stopping a regressive process, the loss of axons, rather than initiating a progressive process, the formation of new axons.

AB - The present study demonstrates that T4 and S2 rat dorsal root axons decrease significantly from birth to adulthood with almost all of the decrease occurring in the first two weeks of life. Dorsal root ganglion cell numbers do not change during this time period. This is thus an example of postnatal axon elimination not associated with death of the cells that give rise to the axons. Presumably this regressive process is important in the formation of the normal adult nervous system. In addition, these findings raise the possibility that certain types of neonatal denervation may increase adult axon numbers by stopping a regressive process, the loss of axons, rather than initiating a progressive process, the formation of new axons.

UR - http://www.scopus.com/inward/record.url?scp=0022707169&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022707169&partnerID=8YFLogxK

M3 - Article

C2 - 3955377

AN - SCOPUS:0022707169

VL - 391

SP - 105

EP - 113

JO - Brain Research

JF - Brain Research

SN - 0006-8993

IS - 1

ER -