Nutrition in burns: Galveston contributions

Noe A. Rodriguez, Marc G. Jeschke, Felicia N. Williams, Lars Peter Kamolz, David N. Herndon

Research output: Contribution to journalReview articlepeer-review

104 Scopus citations

Abstract

Aggressive nutrition support is recommended following severe burn injury. Initially, such injury results in a prolonged and persistent hypermetabolic response mediated by a 10- to 20-fold elevation in plasma catecholamines, cortisol, and inflammatory mediators. This response leads to twice-normal metabolic rates, whole-body catabolism, muscle wasting, and severe cachexia. Thus, it is relevant to review the literature on nutrition in burns to adjust/update treatment. Failure to meet the increased substrate requirements may result in impaired wound healing, multiorgan dysfunction, increased susceptibility to infection, and death. Therefore, aggressive nutrition support is essential to ensure adequate burn care, attenuate the hypermetabolic response, optimize wound healing, minimize devastating catabolism, and reduce morbidity and mortality. Here, the authors provide nutrition recommendations gained from prospective trials, retrospective analyses, and expert opinions based on the authors' practices in Galveston, Texas, and Vienna, Austria.

Original languageEnglish (US)
Pages (from-to)704-714
Number of pages11
JournalJournal of Parenteral and Enteral Nutrition
Volume35
Issue number6
DOIs
StatePublished - Nov 2011

Keywords

  • adult
  • burns
  • critical care
  • enteral nutrition
  • pediatrics
  • trauma
  • wound healing

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

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