Obesity, Systemic Hypertension, and Pulmonary Hypertension: A Tale of Three Diseases

Abdul Wahab, Amit K. Dey, Dhrubajyoti Bandyopadhyay, Veena Katikineni, Rajus Chopra, Karthik S. Vedantam, Mithun Devraj, Anil K. Chowdary, Keron Navarengom, Carl J. Lavie, Anna Kolpakchi, Hani Jneid

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations

Abstract

Cardiovascular disease (CVD), especially ischemic heart disease and stroke, is the major cause of death worldwide, accounting for more than one-third of all deaths annually. Hypertension is the most prevalent and modifiable risk factor of CVD-related deaths. The same is true for obesity, which is currently being recognized as a major global epidemic. The prevalence of obesity in the United States has increased dramatically, from 13.4% in 1960 to 36.5% in 2014, with as much as 70.7% of the American adult population being overweight or obese (CDC). Epidemiological studies have shown that obesity predisposes to hypertension and CVD – with the relationship between markers of obesity and blood pressure being almost linear across different populations. In this review, we discuss systemic and pulmonary hypertension in the context of obesity.

Original languageEnglish (US)
Article number100599
JournalCurrent Problems in Cardiology
Volume46
Issue number3
DOIs
StatePublished - Mar 2021
Externally publishedYes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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