TY - JOUR
T1 - Obesity, Systemic Hypertension, and Pulmonary Hypertension
T2 - A Tale of Three Diseases
AU - Wahab, Abdul
AU - Dey, Amit K.
AU - Bandyopadhyay, Dhrubajyoti
AU - Katikineni, Veena
AU - Chopra, Rajus
AU - Vedantam, Karthik S.
AU - Devraj, Mithun
AU - Chowdary, Anil K.
AU - Navarengom, Keron
AU - Lavie, Carl J.
AU - Kolpakchi, Anna
AU - Jneid, Hani
N1 - Publisher Copyright:
© 2020 Elsevier Inc.
PY - 2021/3
Y1 - 2021/3
N2 - Cardiovascular disease (CVD), especially ischemic heart disease and stroke, is the major cause of death worldwide, accounting for more than one-third of all deaths annually. Hypertension is the most prevalent and modifiable risk factor of CVD-related deaths. The same is true for obesity, which is currently being recognized as a major global epidemic. The prevalence of obesity in the United States has increased dramatically, from 13.4% in 1960 to 36.5% in 2014, with as much as 70.7% of the American adult population being overweight or obese (CDC). Epidemiological studies have shown that obesity predisposes to hypertension and CVD – with the relationship between markers of obesity and blood pressure being almost linear across different populations. In this review, we discuss systemic and pulmonary hypertension in the context of obesity.
AB - Cardiovascular disease (CVD), especially ischemic heart disease and stroke, is the major cause of death worldwide, accounting for more than one-third of all deaths annually. Hypertension is the most prevalent and modifiable risk factor of CVD-related deaths. The same is true for obesity, which is currently being recognized as a major global epidemic. The prevalence of obesity in the United States has increased dramatically, from 13.4% in 1960 to 36.5% in 2014, with as much as 70.7% of the American adult population being overweight or obese (CDC). Epidemiological studies have shown that obesity predisposes to hypertension and CVD – with the relationship between markers of obesity and blood pressure being almost linear across different populations. In this review, we discuss systemic and pulmonary hypertension in the context of obesity.
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U2 - 10.1016/j.cpcardiol.2020.100599
DO - 10.1016/j.cpcardiol.2020.100599
M3 - Review article
C2 - 32560908
AN - SCOPUS:85086518397
SN - 0146-2806
VL - 46
JO - Current Problems in Cardiology
JF - Current Problems in Cardiology
IS - 3
M1 - 100599
ER -