Observations on the effect of levodopa on tardive lingual-facial-buccal dyskinesia

H. L. Klawans; R. R. McKendall

doi:10.1016/0022-510X(71)90087-6

Observations on the effect of levodopa on tardive lingual-facial-buccal dyskinesia

H. L. Klawans, R. R. McKendall

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Abstract

A patient with neuroleptic-induced lingual-facial-buccal dyskinesia and minimal drug-induced Parkinsonism was treated with Levodopa. This markedly worsened her abnormal movements. This observation supports the concept that tardive dyskinesias are related to hypersensitivity of dopaminergic receptors to dopamine. It is suggested that Levodopa should be avoided in such patients.

Original language	English (US)
Pages (from-to)	189-192
Number of pages	4
Journal	Journal of the Neurological Sciences
Volume	14
Issue number	2
DOIs	https://doi.org/10.1016/0022-510X(71)90087-6
State	Published - Oct 1971
Externally published	Yes

ASJC Scopus subject areas

Neurology
Clinical Neurology

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10.1016/0022-510X(71)90087-6

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title = "Observations on the effect of levodopa on tardive lingual-facial-buccal dyskinesia",

abstract = "A patient with neuroleptic-induced lingual-facial-buccal dyskinesia and minimal drug-induced Parkinsonism was treated with Levodopa. This markedly worsened her abnormal movements. This observation supports the concept that tardive dyskinesias are related to hypersensitivity of dopaminergic receptors to dopamine. It is suggested that Levodopa should be avoided in such patients.",

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AB - A patient with neuroleptic-induced lingual-facial-buccal dyskinesia and minimal drug-induced Parkinsonism was treated with Levodopa. This markedly worsened her abnormal movements. This observation supports the concept that tardive dyskinesias are related to hypersensitivity of dopaminergic receptors to dopamine. It is suggested that Levodopa should be avoided in such patients.

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Observations on the effect of levodopa on tardive lingual-facial-buccal dyskinesia

Abstract

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