Ocular Surface Disease in Glaucoma Patients

Purpose: To review the most recent studies in the literature regarding the ocular surface in glaucoma patients and treatment options aimed to reduce ocular surface disease in this population Methods: We performed a literature search in the electronic databases of PubMed CENT RAL, Google Scholar, EMBASE the Register of Controlled Trials, and Ovid MEDLINE using the following terms: “ocular surface”, “dry eye”, “glaucoma”, “selective laser trabeculoplasty”, “glaucoma surgery”, “preservatives”, “preservative free”, “ocular surface disease index”, “tear break up time”, “MMP-9” and “conjunctival hyperemia”. Results: Over the last several years, several studies have demonstrated the changes to the ocular surface in the setting of glaucoma, the best tests for markers of dry eye, and how management can be altered to help address ocular surface disease routinely or in preparation for glaucoma surgery. Conclusion: Ocular surface disease in the glaucoma patient population is widely recognized. It should be addressed to maximize patient compliance and quality of life.