Oligomerization-induced modulation of TPR-MET tyrosine kinase activity

Keyphrases

• Receptor Tyrosine Kinase 100%
• Oligomerization 100%
• Tyrosine Kinase Activity 100%
• Peptide Substrate 50%
• Phosphorylation 33%
• Conformational Change 33%
• C-Met 33%
• Cytoplasmic Domain 33%
• Oncoprotein 33%
• Enzymatic Analysis 33%
• Regulatory Mechanism 16%
• Recombinant 16%
• Kinase Activation 16%
• Kinetic Properties 16%
• Catalytic Efficiency 16%
• Enzymatic Activity 16%
• Dissociation Constant 16%
• Coiled-coil Motif 16%
• Km Value 16%
• Mechanistic Model 16%
• Kinetic Changes 16%
• Substrate Binding 16%
• Kcat 16%
• Structure-based Design 16%
• Nuclear Pore Complex 16%
• Activation Loop 16%
• Binding Efficiency 16%
• ATP-competitive Inhibitors 16%
• Receptor Tyrosine Kinase Inhibitor 16%
• Receptor Heteromers 16%

Biochemistry, Genetics and Molecular Biology

• Receptor Tyrosine Kinase 100%
• Oligomerization 100%
• Tyrosine Kinase 100%
• Adenosine Triphosphate 71%
• Conformational Change 28%
• Enzyme 14%
• Protein Kinase C 14%
• Catalytic Efficiency 14%
• Enzyme Activity 14%
• Coiled Coil 14%
• Competitive Inhibition 14%
• Dissociation Constant 14%
• Turnover Number 14%
• Nuclear Pore Complex 14%
• Enzyme Phosphorylation 14%
• Receptor Tyrosine Kinase Inhibitors 14%