Abstract
A 4-month-old male infant had a 2-month history of an exfoliative erythroderma and alopecia. Recurrent mucosal infections, diffuse lymphadenopathy, hepatosplenomegaly, lymphocytosis and eosinophilia, anemia, and failure to thrive later developed. Investigation revealed a combined immunodeficiency with T cells of an unusual phenotype in his peripheral blood, skin, and lymph nodes. Our patient's clinical manifestations most closely resemble Omenn's syndrome, a rare form of autosomal recessive combined immunodeficiency.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 442-446 |
| Number of pages | 5 |
| Journal | Journal of the American Academy of Dermatology |
| Volume | 25 |
| Issue number | 2 II SUPPL. |
| State | Published - 1991 |
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ASJC Scopus subject areas
- Dermatology
Cite this
Omenn's syndrome and related combined immunodeficiency syndromes : Diagnostic considerations in infants with persistent erythroderma and failure to thrive. / Pupo, R. A.; Tyring, S. K.; Raimer, Sharon; Wirt, D. P.; Brooks, E. G.; Goldblum, R. M.
In: Journal of the American Academy of Dermatology, Vol. 25, No. 2 II SUPPL., 1991, p. 442-446.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Omenn's syndrome and related combined immunodeficiency syndromes
T2 - Diagnostic considerations in infants with persistent erythroderma and failure to thrive
AU - Pupo, R. A.
AU - Tyring, S. K.
AU - Raimer, Sharon
AU - Wirt, D. P.
AU - Brooks, E. G.
AU - Goldblum, R. M.
PY - 1991
Y1 - 1991
N2 - A 4-month-old male infant had a 2-month history of an exfoliative erythroderma and alopecia. Recurrent mucosal infections, diffuse lymphadenopathy, hepatosplenomegaly, lymphocytosis and eosinophilia, anemia, and failure to thrive later developed. Investigation revealed a combined immunodeficiency with T cells of an unusual phenotype in his peripheral blood, skin, and lymph nodes. Our patient's clinical manifestations most closely resemble Omenn's syndrome, a rare form of autosomal recessive combined immunodeficiency.
AB - A 4-month-old male infant had a 2-month history of an exfoliative erythroderma and alopecia. Recurrent mucosal infections, diffuse lymphadenopathy, hepatosplenomegaly, lymphocytosis and eosinophilia, anemia, and failure to thrive later developed. Investigation revealed a combined immunodeficiency with T cells of an unusual phenotype in his peripheral blood, skin, and lymph nodes. Our patient's clinical manifestations most closely resemble Omenn's syndrome, a rare form of autosomal recessive combined immunodeficiency.
UR - http://www.scopus.com/inward/record.url?scp=0025856973&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0025856973&partnerID=8YFLogxK
M3 - Article
VL - 25
SP - 442
EP - 446
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
SN - 0190-9622
IS - 2 II SUPPL.
ER -