On the cooperative binding of large ligands to a one-dimensional homogeneous lattice: the generalized three-state lattice model.

Wlodzimierz Bujalowski, T. M. Lohman, C. F. Anderson

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Abstract

We present the general secular equation for three-state lattice models for the cooperative binding of large ligands to a one-dimensional lattice. In addition, a closed-form expression for the isotherm is also obtained, that can be used with all values of the cooperativity parameter omega(0 less than omega less than infinity) thus eliminating the need for multiple equations.

Original languageEnglish (US)
Pages (from-to)1637-1643
Number of pages7
JournalBiopolymers - Peptide Science Section
Volume28
Issue number9
StatePublished - Sep 1989
Externally publishedYes

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Isotherms
Ligands

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Biophysics

Cite this

On the cooperative binding of large ligands to a one-dimensional homogeneous lattice : the generalized three-state lattice model. / Bujalowski, Wlodzimierz; Lohman, T. M.; Anderson, C. F.

In: Biopolymers - Peptide Science Section, Vol. 28, No. 9, 09.1989, p. 1637-1643.

Research output: Contribution to journalArticle

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