On the cooperative binding of large ligands to a one‐dimensional homogeneous lattice: The generalized three‐state lattice model

Wlodzimierz Bujalowski, Timothy M. Lohman, Charles F. Anderson

    Research output: Contribution to journalArticlepeer-review

    71 Scopus citations

    Abstract

    We present the general secular equation for three‐state lattice models for the cooperative binding of large ligands to a one‐dimensional lattice. In addition, a closed‐form expression for the isotherm is also obtained, that can be used with all values of the cooperativity parameter ω(0 < ω < ∞) thus eliminating the need for multiple equations.

    Original languageEnglish (US)
    Pages (from-to)1637-1643
    Number of pages7
    JournalBiopolymers
    Volume28
    Issue number9
    DOIs
    StatePublished - Sep 1989

    ASJC Scopus subject areas

    • Biophysics
    • Biochemistry
    • Biomaterials
    • Organic Chemistry

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