On the cooperative binding of large ligands to a one‐dimensional homogeneous lattice: The generalized three‐state lattice model

Wlodzimierz Bujalowski, Timothy M. Lohman, Charles F. Anderson

Research output: Contribution to journalArticle

71 Scopus citations

Abstract

We present the general secular equation for three‐state lattice models for the cooperative binding of large ligands to a one‐dimensional lattice. In addition, a closed‐form expression for the isotherm is also obtained, that can be used with all values of the cooperativity parameter ω(0 < ω < ∞) thus eliminating the need for multiple equations.

Original languageEnglish (US)
Pages (from-to)1637-1643
Number of pages7
JournalBiopolymers
Volume28
Issue number9
DOIs
StatePublished - Sep 1989
Externally publishedYes

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Biomaterials
  • Organic Chemistry

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