On the cooperative binding of large ligands to a one‐dimensional homogeneous lattice: The generalized three‐state lattice model

Wlodzimierz Bujalowski; Timothy M. Lohman; Charles F. Anderson

doi:10.1002/bip.360280912

On the cooperative binding of large ligands to a one‐dimensional homogeneous lattice: The generalized three‐state lattice model

Wlodzimierz Bujalowski
, Timothy M. Lohman
, Charles F. Anderson

Biochemistry & Molecular Biology

Research output: Contribution to journal › Article › peer-review

75 Scopus citations

Abstract

We present the general secular equation for three‐state lattice models for the cooperative binding of large ligands to a one‐dimensional lattice. In addition, a closed‐form expression for the isotherm is also obtained, that can be used with all values of the cooperativity parameter ω(0 < ω < ∞) thus eliminating the need for multiple equations.

Original language	English (US)
Pages (from-to)	1637-1643
Number of pages	7
Journal	Biopolymers
Volume	28
Issue number	9
DOIs	https://doi.org/10.1002/bip.360280912
State	Published - Sep 1989

ASJC Scopus subject areas

Biophysics
Biochemistry
Biomaterials
Organic Chemistry

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10.1002/bip.360280912

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title = "On the cooperative binding of large ligands to a one‐dimensional homogeneous lattice: The generalized three‐state lattice model",

abstract = "We present the general secular equation for three‐state lattice models for the cooperative binding of large ligands to a one‐dimensional lattice. In addition, a closed‐form expression for the isotherm is also obtained, that can be used with all values of the cooperativity parameter ω(0 < ω < ∞) thus eliminating the need for multiple equations.",

author = "Wlodzimierz Bujalowski and Lohman, \{Timothy M.\} and Anderson, \{Charles F.\}",

year = "1989",

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T2 - The generalized three‐state lattice model

AU - Bujalowski, Wlodzimierz

AU - Lohman, Timothy M.

AU - Anderson, Charles F.

PY - 1989/9

Y1 - 1989/9

N2 - We present the general secular equation for three‐state lattice models for the cooperative binding of large ligands to a one‐dimensional lattice. In addition, a closed‐form expression for the isotherm is also obtained, that can be used with all values of the cooperativity parameter ω(0 < ω < ∞) thus eliminating the need for multiple equations.

AB - We present the general secular equation for three‐state lattice models for the cooperative binding of large ligands to a one‐dimensional lattice. In addition, a closed‐form expression for the isotherm is also obtained, that can be used with all values of the cooperativity parameter ω(0 < ω < ∞) thus eliminating the need for multiple equations.

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U2 - 10.1002/bip.360280912

DO - 10.1002/bip.360280912

M3 - Article

C2 - 2775853

AN - SCOPUS:0024730670

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JO - Biopolymers

JF - Biopolymers

IS - 9

ER -

On the cooperative binding of large ligands to a one‐dimensional homogeneous lattice: The generalized three‐state lattice model

Abstract

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