One day of moderate energy deficit reduces fasting and postprandial triacylglycerolemia in women: The role of calorie restriction and exercise

Maria Maraki, Faidon Magkos, Nektarios Christodoulou, Niki Aggelopoulou, Katerina P. Skenderi, Demosthenes Panagiotakos, Stavros A. Kavouras, Labros S. Sidossis

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

Background & aims: Fasting and postprandial hypertriacylglycerolemia are important cardiovascular risk factors in women. We sought to examine the effects of acute (1 day), moderate (∼2 MJ) energy deficit induced by calorie restriction, exercise, or combination of both on fasting and postprandial triacylglycerol (TAG) metabolism in women. Methods: Six healthy premenopausal women performed four oral fat tolerance tests in the morning after a day of a) rest (control), b) calorie restriction (∼2 MJ), c) exercise (net deficit of ∼2 MJ) and d) calorie restriction-plus-exercise (total energy deficit of ∼2 MJ). Results: All energy deficit trials significantly reduced fasting and postprandial total plasma TAG concentrations by 15-23% and 12-23%, respectively, and triacylglycerol-rich lipoprotein TAG concentrations by 37-43% and 25-39%, respectively, compared with the control condition (P<0.05). Postprandial, but not fasting, total TAG concentrations were ∼12% lower after exercise compared with diet-induced energy deficit (P=0.05). Conclusions: Acute, moderate energy deficit independently of its origin (i.e. diet or exercise or combination of both) reduces fasting and postprandial triacylglycerolemia in women. Exercise elicits a somewhat greater effect than calorie restriction in the postprandial state. The acute effect of diet and exercise should be taken into account when studying the long-term effects of weight loss and exercise training on TAG metabolism.

Original languageEnglish (US)
Pages (from-to)459-463
Number of pages5
JournalClinical Nutrition
Volume29
Issue number4
DOIs
StatePublished - Aug 1 2010

Keywords

  • Diet
  • Lipid metabolism
  • Physical activity
  • Triglyceride

ASJC Scopus subject areas

  • Nutrition and Dietetics
  • Critical Care and Intensive Care Medicine

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    Maraki, M., Magkos, F., Christodoulou, N., Aggelopoulou, N., Skenderi, K. P., Panagiotakos, D., Kavouras, S. A., & Sidossis, L. S. (2010). One day of moderate energy deficit reduces fasting and postprandial triacylglycerolemia in women: The role of calorie restriction and exercise. Clinical Nutrition, 29(4), 459-463. https://doi.org/10.1016/j.clnu.2009.10.007