O’nyong-nyong fever: a neglected mosquito-borne viral disease

Giovanni Rezza; Rubing Chen; Scott C. Weaver

doi:10.1080/20477724.2017.1355431

O’nyong-nyong fever: a neglected mosquito-borne viral disease

Giovanni Rezza, Rubing Chen, Scott C. Weaver

Microbiology And Immunology

Research output: Contribution to journal › Review article › peer-review

80 Scopus citations

Abstract

O’nyong nyong virus (ONNV), a mosquito-borne Alphavirus, is primarily transmitted through the bite of Anopheles funestus and Anopheles gambiae mosquitoes, which are also malaria parasite vectors in Africa. The virus, first isolated in Uganda in 1959, is endemic in sub-Saharan Africa and has caused several major outbreaks both in West and East Africa. ONNV fever, characterized by severe arthralgia, is similar to chikungunya fever, with the exception of cervical lymphadenitis, which is peculiar to the former. Prevention measures do not differ from those adopted against malaria parasite transmission. Effective vaccines and drugs are not available, but animal models suggest that vaccine candidates against CHIKV may also confer protection against ONNV.

Original language	English (US)
Pages (from-to)	271-275
Number of pages	5
Journal	Pathogens and Global Health
Volume	111
Issue number	6
DOIs	https://doi.org/10.1080/20477724.2017.1355431
State	Published - Aug 18 2017

Keywords

O’nyong-nyong
alphavirus
chikungunya
epidemiology

ASJC Scopus subject areas

Parasitology
Microbiology
Public Health, Environmental and Occupational Health
Infectious Diseases

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10.1080/20477724.2017.1355431

Cite this

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title = "O{\textquoteright}nyong-nyong fever: a neglected mosquito-borne viral disease",

abstract = "O{\textquoteright}nyong nyong virus (ONNV), a mosquito-borne Alphavirus, is primarily transmitted through the bite of Anopheles funestus and Anopheles gambiae mosquitoes, which are also malaria parasite vectors in Africa. The virus, first isolated in Uganda in 1959, is endemic in sub-Saharan Africa and has caused several major outbreaks both in West and East Africa. ONNV fever, characterized by severe arthralgia, is similar to chikungunya fever, with the exception of cervical lymphadenitis, which is peculiar to the former. Prevention measures do not differ from those adopted against malaria parasite transmission. Effective vaccines and drugs are not available, but animal models suggest that vaccine candidates against CHIKV may also confer protection against ONNV.",

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AB - O’nyong nyong virus (ONNV), a mosquito-borne Alphavirus, is primarily transmitted through the bite of Anopheles funestus and Anopheles gambiae mosquitoes, which are also malaria parasite vectors in Africa. The virus, first isolated in Uganda in 1959, is endemic in sub-Saharan Africa and has caused several major outbreaks both in West and East Africa. ONNV fever, characterized by severe arthralgia, is similar to chikungunya fever, with the exception of cervical lymphadenitis, which is peculiar to the former. Prevention measures do not differ from those adopted against malaria parasite transmission. Effective vaccines and drugs are not available, but animal models suggest that vaccine candidates against CHIKV may also confer protection against ONNV.

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O’nyong-nyong fever: a neglected mosquito-borne viral disease

Abstract

Keywords

ASJC Scopus subject areas

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