O’nyong-nyong fever

a neglected mosquito-borne viral disease

Giovanni Rezza, Rubing Chen, Scott Weaver

Research output: Contribution to journalReview article

9 Citations (Scopus)

Abstract

O’nyong nyong virus (ONNV), a mosquito-borne Alphavirus, is primarily transmitted through the bite of Anopheles funestus and Anopheles gambiae mosquitoes, which are also malaria parasite vectors in Africa. The virus, first isolated in Uganda in 1959, is endemic in sub-Saharan Africa and has caused several major outbreaks both in West and East Africa. ONNV fever, characterized by severe arthralgia, is similar to chikungunya fever, with the exception of cervical lymphadenitis, which is peculiar to the former. Prevention measures do not differ from those adopted against malaria parasite transmission. Effective vaccines and drugs are not available, but animal models suggest that vaccine candidates against CHIKV may also confer protection against ONNV.

Original languageEnglish (US)
Pages (from-to)271-275
Number of pages5
JournalPathogens and Global Health
Volume111
Issue number6
DOIs
StatePublished - Aug 18 2017

Fingerprint

O'nyong-nyong Virus
Virus Diseases
Culicidae
Fever
Malaria
Parasites
Vaccines
Alphavirus
Anopheles gambiae
Eastern Africa
Lymphadenitis
Anopheles
Western Africa
Uganda
Africa South of the Sahara
Arthralgia
Bites and Stings
Disease Outbreaks
Animal Models
Viruses

Keywords

  • alphavirus
  • chikungunya
  • epidemiology
  • O’nyong-nyong

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Cite this

O’nyong-nyong fever : a neglected mosquito-borne viral disease. / Rezza, Giovanni; Chen, Rubing; Weaver, Scott.

In: Pathogens and Global Health, Vol. 111, No. 6, 18.08.2017, p. 271-275.

Research output: Contribution to journalReview article

Rezza, Giovanni ; Chen, Rubing ; Weaver, Scott. / O’nyong-nyong fever : a neglected mosquito-borne viral disease. In: Pathogens and Global Health. 2017 ; Vol. 111, No. 6. pp. 271-275.
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