Opportunities and challenges for immunosuppression in the context of pig-to-human xenotransplantation

Guillaume Onyeaghala; Casey R. Dorr; Ajay K. Israni

doi:10.1016/j.medj.2024.07.017

Opportunities and challenges for immunosuppression in the context of pig-to-human xenotransplantation

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

The transplantation of organ(s) across species may alleviate the shortage of available donor kidneys for an ever-growing number of patients on transplant waiting lists. However, this potential remains limited by uncharacterized physiologic and immune effects of xenotransplants in recipients, which Pan et al.¹ investigated in the current study.

Original language	English (US)
Pages (from-to)	842-844
Number of pages	3
Journal	Med
Volume	5
Issue number	8
DOIs	https://doi.org/10.1016/j.medj.2024.07.017
State	Published - Aug 9 2024
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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10.1016/j.medj.2024.07.017

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title = "Opportunities and challenges for immunosuppression in the context of pig-to-human xenotransplantation",

abstract = "The transplantation of organ(s) across species may alleviate the shortage of available donor kidneys for an ever-growing number of patients on transplant waiting lists. However, this potential remains limited by uncharacterized physiologic and immune effects of xenotransplants in recipients, which Pan et al.1 investigated in the current study.",

author = "Guillaume Onyeaghala and Dorr, \{Casey R.\} and Israni, \{Ajay K.\}",

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AU - Onyeaghala, Guillaume

AU - Dorr, Casey R.

AU - Israni, Ajay K.

PY - 2024/8/9

Y1 - 2024/8/9

N2 - The transplantation of organ(s) across species may alleviate the shortage of available donor kidneys for an ever-growing number of patients on transplant waiting lists. However, this potential remains limited by uncharacterized physiologic and immune effects of xenotransplants in recipients, which Pan et al.1 investigated in the current study.

AB - The transplantation of organ(s) across species may alleviate the shortage of available donor kidneys for an ever-growing number of patients on transplant waiting lists. However, this potential remains limited by uncharacterized physiologic and immune effects of xenotransplants in recipients, which Pan et al.1 investigated in the current study.

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UR - https://www.scopus.com/pages/publications/85200413314#tab=citedBy

U2 - 10.1016/j.medj.2024.07.017

DO - 10.1016/j.medj.2024.07.017

M3 - Comment/debate

C2 - 39127030

AN - SCOPUS:85200413314

SN - 2666-6359

VL - 5

SP - 842

EP - 844

JO - Med

JF - Med

IS - 8

ER -

Opportunities and challenges for immunosuppression in the context of pig-to-human xenotransplantation

Abstract

ASJC Scopus subject areas

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