Optical coherence tomography angiography artifacts in retinal pigment epithelial detachment

Ricardo N. Louzada, Talisa E. de Carlo, Mehreen Adhi, Eduardo A. Novais, Mary K. Durbin, Emily Cole, Mark Lane, Omid Moghimi, Malvika Arya, Marco Bonini Filho, Andre J. Witkin, Caroline R. Baumal, Marcos Ávila, Jay S. Duker, Nadia K. Waheed

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Objective To describe optical coherence tomography angiography (OCTA) reflectance artifacts secondary to retinal pigment epithelial detachment (RPED). Design Retrospective review. Methods Four eyes from 4 subjects were included. Three presented with RPED and 1 eye was a normal control. Two eyes diagnosed with RPED and the normal eye were evaluated using en face OCTA centred at the fovea acquired using the RTVue XR Avanti (Optovue Inc). In the third eye with RPED, OCTA imaging was performed using a CIRRUS 5000 prototype modified to do OCTA imaging on a spectral domain OCT platform provided by Carl Zeiss Meditec, Inc. The segmented OCTA angiograms were overlaid to determine if the flow patterns seen at the edge of the RPEDs were due to reflectance from the inner retinal vessels, also known as “decorrelation tails.” Results OCTA projection artifacts were noted when segmentation lines intersected with the boundary of the RPED. The overlaid segmented OCTA from the 3 RPED eyes imaged using each system revealed the same vasculature pattern at the edges of the RPED as that of the inner retina, demonstrating the “decorrelation tails” artifact, which caused the RPED to appear as a bright ring on the segmented OCTA. Conclusions OCTA images are susceptible to various known artifacts. This series describes the impact of the projection artifact seen at the edges of an RPED that simulates appearance of flow but is actually due to reflectance of the inner retinal vasculature on the RPED.

Original languageEnglish (US)
Pages (from-to)419-424
Number of pages6
JournalCanadian Journal of Ophthalmology
Volume52
Issue number4
DOIs
StatePublished - Aug 2017
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology

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