Optimal management of gout in older patients.

Emilio Gonzalez, S. B. Miller, C. A. Agudelo

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Gout in older patients tends to be sub-acute to chronic, often tophaceous, polyarticular, erosive, symmetrical, and causes persistent, recurrent and chronic arthritis. Clinically, it may closely mimic rheumatoid arthritis; thus, a correct diagnosis requires a high index of clinical suspicion and the identification of uric acid crystals. An optimal therapeutic strategy for most older patients with chronic tophaceous gout could involve the following: avoidance of alcohol and diuretic use if possible; avoidance of long term nonsteroidal anti-inflammatory drug (NSAID) therapy; use of short term corticosteroids (systemic or intra-articular) for acute exacerbations; prophylactic colchicine daily or every other day according to the degree of renal dysfunction present; and long term allopurinol therapy in dosages adjusted to the degree of hyperuricaemia and renal dysfunction.

Original languageEnglish (US)
Pages (from-to)128-134
Number of pages7
JournalDrugs & aging
Volume4
Issue number2
StatePublished - Feb 1994
Externally publishedYes

Fingerprint

Gout
Kidney
Allopurinol
Colchicine
Uric Acid
Diuretics
Arthritis
Rheumatoid Arthritis
Adrenal Cortex Hormones
Anti-Inflammatory Agents
Joints
Alcohols
Drug Therapy
Therapeutics

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Pharmacology

Cite this

Gonzalez, E., Miller, S. B., & Agudelo, C. A. (1994). Optimal management of gout in older patients. Drugs & aging, 4(2), 128-134.

Optimal management of gout in older patients. / Gonzalez, Emilio; Miller, S. B.; Agudelo, C. A.

In: Drugs & aging, Vol. 4, No. 2, 02.1994, p. 128-134.

Research output: Contribution to journalArticle

Gonzalez, E, Miller, SB & Agudelo, CA 1994, 'Optimal management of gout in older patients.', Drugs & aging, vol. 4, no. 2, pp. 128-134.
Gonzalez E, Miller SB, Agudelo CA. Optimal management of gout in older patients. Drugs & aging. 1994 Feb;4(2):128-134.
Gonzalez, Emilio ; Miller, S. B. ; Agudelo, C. A. / Optimal management of gout in older patients. In: Drugs & aging. 1994 ; Vol. 4, No. 2. pp. 128-134.
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