Optimized production and immunogenicity of an insect virus-based chikungunya virus candidate vaccine in cell culture and animal models

Immunology and Microbiology

• Immunogenicity 100%
• Memory B Cell 100%
• Cell Culture 100%
• Adaptive Immune System 100%
• Cytotoxic T-Cell 100%
• Chikungunya Virus 100%
• Insect Virus 100%
• Virus 100%
• T-Helper Cell 50%
• Antigen-Presenting Cell 50%
• Sensitization 50%
• Immunoglobulin M 50%
• Antigen Presenting Cell 50%
• Cytokine Response 50%
• Hypersensitive Response 50%
• Immunoglobulin G 50%
• CD8 50%
• In Vitro 50%

Keyphrases

• Immunogenicity 100%
• Vaccine Antigen 100%
• Cell Culture 100%
• Chikungunya Virus (CHIKV) 100%
• Insect Virus 100%
• Optimized Production 100%
• Live Attenuated 16%
• Adaptive Immunity 16%
• CD8+ T Cells 16%
• Memory B Cells 16%
• Inducer 8%
• Innate Immunity 8%
• Cell Response 8%
• CD4+ T 8%
• Vaccine Candidate 8%
• IgM Antibody 8%
• In Vivo Exposure 8%
• Serum IgE 8%
• Revaccination 8%
• Antigen-presenting Cells 8%
• Mosquito Cells 8%
• Induced Immunity 8%
• IgG Antibody 8%
• Cytokine Response 8%
• Chimeric Virus 8%
• CD8+ 8%
• Specific IgM 8%
• Antiviral Cytokines 8%
• Viral Stock 8%
• Two-step Procedure 8%
• Cytokine Activation 8%
• Eilat 8%
• Robust Adaptive 8%
• Sensitization Study 8%