Abstract
Despite improvements in medical and surgical treatment of intestinal failure, intestine transplant continues to play an important role. In 2017, 109 intestine transplants were performed, 62 in adults and 47 in children, reflecting the changed age distribution over the past decade of candidates waitlisted for intestine and intestine-liver transplant from largely pediatric to increasing proportions of adults. In 2017, 56.0% of candidates on the intestine list at any time during the year were aged younger than 18 years, with a decrease over time in those aged younger than 6 years and an increase in those aged 6-17 years. Adults accounted for 44.0% of candidates on the list at any time during the year, with an increase since 2013 in those aged 18-34 years and a decrease in those aged 35 years or older. By age, the pretransplant mortality rate was highest for adult candidates at 7.9 per 100 waitlist-years and lowest for pediatric candidates at 3.7 per 100 waitlist-years. Patient survival varied by age and type of transplant, and was lowest for adult intestine-liver recipients (1- and 5-year survival 66.7% and 42.6%, respectively) and highest for pediatric intestine recipients (1- and 5-year survival 86.2% and 75.4%, respectively).
Original language | English (US) |
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Pages (from-to) | 284-322 |
Number of pages | 39 |
Journal | American Journal of Transplantation |
Volume | 19 |
DOIs | |
State | Published - Feb 2019 |
Externally published | Yes |
Keywords
- Intestinal failure
- intestine transplant
- intestine-liver transplant
- waiting list
ASJC Scopus subject areas
- Immunology and Allergy
- Transplantation
- Pharmacology (medical)