OPTN/SRTR 2021 Annual Data Report: Vascularized Composite Allograft

J. Andres Hernandez; Guiliano Testa; Hani I. Naga; Kaylyn B. Pogson; Jonathan M. Miller; Sarah E. Booker; Jesse Howell; Kelley Poff; Liza Johannesson; Ajay K. Israni; Jon J. Snyder; Linda C. Cendales

doi:10.1016/j.ajt.2023.02.012

OPTN/SRTR 2021 Annual Data Report: Vascularized Composite Allograft

J. Andres Hernandez
, Guiliano Testa
, Hani I. Naga
, Kaylyn B. Pogson
, Jonathan M. Miller
, Sarah E. Booker
, Jesse Howell
, Kelley Poff
, Liza Johannesson
, Ajay K. Israni
, Jon J. Snyder
, Linda C. Cendales

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Year 2020 marked the first OPTN/SRTR Annual Data Report that included a chapter on vascularized composite allograft (VCA), which encompassed reviews of data collected between 2014 (when VCA was included in the Final Rule) and 2020. The present Annual Data Report shows that the number of VCA recipients in the United States continues to be small and trended downward in 2021. While data continue to be limited by sample size, trends continue to show a predominance in White, young/middle-aged, male recipients. Similar to the 2020 report, eight uterus and one non-uterus VCA graft failures were reported from 2014 through 2021. Critical to advancement of VCA transplantation will be the standardization of definitions, protocols, and outcome measures for the different VCA types. Like intestinal transplants, it is likely that VCA transplants will be concentrated and performed at referral transplant centers.

Original language	English (US)
Pages (from-to)	S523-S545
Journal	American Journal of Transplantation
Volume	23
Issue number	2S1
DOIs	https://doi.org/10.1016/j.ajt.2023.02.012
State	Published - Feb 1 2023
Externally published	Yes

Keywords

Abdominal wall transplant
face transplant
multiorgan transplant
upper limb transplant
vascularized composite allograft (VCA)

ASJC Scopus subject areas

Immunology and Allergy
Transplantation
Pharmacology (medical)

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10.1016/j.ajt.2023.02.012

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@article{984c8033a772485c97524d63576955a5,

title = "OPTN/SRTR 2021 Annual Data Report: Vascularized Composite Allograft",

abstract = "Year 2020 marked the first OPTN/SRTR Annual Data Report that included a chapter on vascularized composite allograft (VCA), which encompassed reviews of data collected between 2014 (when VCA was included in the Final Rule) and 2020. The present Annual Data Report shows that the number of VCA recipients in the United States continues to be small and trended downward in 2021. While data continue to be limited by sample size, trends continue to show a predominance in White, young/middle-aged, male recipients. Similar to the 2020 report, eight uterus and one non-uterus VCA graft failures were reported from 2014 through 2021. Critical to advancement of VCA transplantation will be the standardization of definitions, protocols, and outcome measures for the different VCA types. Like intestinal transplants, it is likely that VCA transplants will be concentrated and performed at referral transplant centers.",

keywords = "Abdominal wall transplant, face transplant, multiorgan transplant, upper limb transplant, vascularized composite allograft (VCA)",

author = "Hernandez, \{J. Andres\} and Guiliano Testa and Naga, \{Hani I.\} and Pogson, \{Kaylyn B.\} and Miller, \{Jonathan M.\} and Booker, \{Sarah E.\} and Jesse Howell and Kelley Poff and Liza Johannesson and Israni, \{Ajay K.\} and Snyder, \{Jon J.\} and Cendales, \{Linda C.\}",

note = "Publisher Copyright: Copyright {\textcopyright} 2023. Published by Elsevier Inc.",

year = "2023",

month = feb,

day = "1",

doi = "10.1016/j.ajt.2023.02.012",

language = "English (US)",

volume = "23",

pages = "S523--S545",

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publisher = "Elsevier B.V.",

number = "2S1",

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TY - JOUR

T1 - OPTN/SRTR 2021 Annual Data Report

T2 - Vascularized Composite Allograft

AU - Hernandez, J. Andres

AU - Testa, Guiliano

AU - Naga, Hani I.

AU - Pogson, Kaylyn B.

AU - Miller, Jonathan M.

AU - Booker, Sarah E.

AU - Howell, Jesse

AU - Poff, Kelley

AU - Johannesson, Liza

AU - Israni, Ajay K.

AU - Snyder, Jon J.

AU - Cendales, Linda C.

PY - 2023/2/1

Y1 - 2023/2/1

N2 - Year 2020 marked the first OPTN/SRTR Annual Data Report that included a chapter on vascularized composite allograft (VCA), which encompassed reviews of data collected between 2014 (when VCA was included in the Final Rule) and 2020. The present Annual Data Report shows that the number of VCA recipients in the United States continues to be small and trended downward in 2021. While data continue to be limited by sample size, trends continue to show a predominance in White, young/middle-aged, male recipients. Similar to the 2020 report, eight uterus and one non-uterus VCA graft failures were reported from 2014 through 2021. Critical to advancement of VCA transplantation will be the standardization of definitions, protocols, and outcome measures for the different VCA types. Like intestinal transplants, it is likely that VCA transplants will be concentrated and performed at referral transplant centers.

AB - Year 2020 marked the first OPTN/SRTR Annual Data Report that included a chapter on vascularized composite allograft (VCA), which encompassed reviews of data collected between 2014 (when VCA was included in the Final Rule) and 2020. The present Annual Data Report shows that the number of VCA recipients in the United States continues to be small and trended downward in 2021. While data continue to be limited by sample size, trends continue to show a predominance in White, young/middle-aged, male recipients. Similar to the 2020 report, eight uterus and one non-uterus VCA graft failures were reported from 2014 through 2021. Critical to advancement of VCA transplantation will be the standardization of definitions, protocols, and outcome measures for the different VCA types. Like intestinal transplants, it is likely that VCA transplants will be concentrated and performed at referral transplant centers.

KW - Abdominal wall transplant

KW - face transplant

KW - multiorgan transplant

KW - upper limb transplant

KW - vascularized composite allograft (VCA)

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U2 - 10.1016/j.ajt.2023.02.012

DO - 10.1016/j.ajt.2023.02.012

M3 - Article

C2 - 37132342

AN - SCOPUS:85158024066

SN - 1600-6135

VL - 23

SP - S523-S545

JO - American Journal of Transplantation

JF - American Journal of Transplantation

IS - 2S1

ER -

OPTN/SRTR 2021 Annual Data Report: Vascularized Composite Allograft

Abstract

Keywords

ASJC Scopus subject areas

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