Abstract
Optoacoustic diagnostics is a novel imaging modality based on detection and analysis of optoacoustic waves induced in tissues. We proposed and tested in animal and clinical studies a number of important optoacoustic diagnostic applications such as diagnostics of cerebral hypoxia, circulatory shock, anemia, thermotherapy monitoring, as well as breast cancer and hematoma detection. Our initial studies were performed with OPO-based systems. Recently, we developed and built FDA-compliant, multi-wavelength, fiber-coupled, highly-compact laser diode optoacoustic systems for imaging, monitoring, and sensing. To provide optoacoustic detection with high SNR, we developed ultra-sensitive optoacoustic probes that incorporate light delivery systems and wide-band acoustic sensors. This optoacoustic instrumentation allows for sensitive detection of optoacoustic signals from small tumors, native, coagulated and frozen tissues, intracranial hematomas, cerebral blood vessels such as the superior sagittal sinus, central veins such as the internal jugular vein, peripheral veins and arteries. We demonstrated also other examples of imaging, sensing, and monitoring with the optoacoustic instrumentation developed by our group including automatic, real-time, continuous measurements of blood oxygenation with high accuracy.
| Original language | English (US) |
|---|---|
| Title of host publication | Proceedings - International Conference Laser Optics 2018, ICLO 2018 |
| Publisher | Institute of Electrical and Electronics Engineers Inc. |
| Number of pages | 1 |
| ISBN (Print) | 9781538636121 |
| DOIs | |
| State | Published - Aug 13 2018 |
| Event | 2018 International Conference Laser Optics, ICLO 2018 - St. Petersburg, Russian Federation Duration: Jun 4 2018 → Jun 8 2018 |
Other
| Other | 2018 International Conference Laser Optics, ICLO 2018 |
|---|---|
| Country | Russian Federation |
| City | St. Petersburg |
| Period | 6/4/18 → 6/8/18 |
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Keywords
- Diagnostics
- Imaging
- Monitoring
- Photoacoustic
- Ptoacoustic
- Therapy
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Atomic and Molecular Physics, and Optics
Cite this
Optoacoustic diagnostic platform : Principles, instrumentation, and applications. / Esenaliev, Rinat.
Proceedings - International Conference Laser Optics 2018, ICLO 2018. Institute of Electrical and Electronics Engineers Inc., 2018. 8435473.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Optoacoustic diagnostic platform
T2 - Principles, instrumentation, and applications
AU - Esenaliev, Rinat
PY - 2018/8/13
Y1 - 2018/8/13
N2 - Optoacoustic diagnostics is a novel imaging modality based on detection and analysis of optoacoustic waves induced in tissues. We proposed and tested in animal and clinical studies a number of important optoacoustic diagnostic applications such as diagnostics of cerebral hypoxia, circulatory shock, anemia, thermotherapy monitoring, as well as breast cancer and hematoma detection. Our initial studies were performed with OPO-based systems. Recently, we developed and built FDA-compliant, multi-wavelength, fiber-coupled, highly-compact laser diode optoacoustic systems for imaging, monitoring, and sensing. To provide optoacoustic detection with high SNR, we developed ultra-sensitive optoacoustic probes that incorporate light delivery systems and wide-band acoustic sensors. This optoacoustic instrumentation allows for sensitive detection of optoacoustic signals from small tumors, native, coagulated and frozen tissues, intracranial hematomas, cerebral blood vessels such as the superior sagittal sinus, central veins such as the internal jugular vein, peripheral veins and arteries. We demonstrated also other examples of imaging, sensing, and monitoring with the optoacoustic instrumentation developed by our group including automatic, real-time, continuous measurements of blood oxygenation with high accuracy.
AB - Optoacoustic diagnostics is a novel imaging modality based on detection and analysis of optoacoustic waves induced in tissues. We proposed and tested in animal and clinical studies a number of important optoacoustic diagnostic applications such as diagnostics of cerebral hypoxia, circulatory shock, anemia, thermotherapy monitoring, as well as breast cancer and hematoma detection. Our initial studies were performed with OPO-based systems. Recently, we developed and built FDA-compliant, multi-wavelength, fiber-coupled, highly-compact laser diode optoacoustic systems for imaging, monitoring, and sensing. To provide optoacoustic detection with high SNR, we developed ultra-sensitive optoacoustic probes that incorporate light delivery systems and wide-band acoustic sensors. This optoacoustic instrumentation allows for sensitive detection of optoacoustic signals from small tumors, native, coagulated and frozen tissues, intracranial hematomas, cerebral blood vessels such as the superior sagittal sinus, central veins such as the internal jugular vein, peripheral veins and arteries. We demonstrated also other examples of imaging, sensing, and monitoring with the optoacoustic instrumentation developed by our group including automatic, real-time, continuous measurements of blood oxygenation with high accuracy.
KW - Diagnostics
KW - Imaging
KW - Monitoring
KW - Photoacoustic
KW - Ptoacoustic
KW - Therapy
UR - http://www.scopus.com/inward/record.url?scp=85052541505&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85052541505&partnerID=8YFLogxK
U2 - 10.1109/LO.2018.8435473
DO - 10.1109/LO.2018.8435473
M3 - Conference contribution
AN - SCOPUS:85052541505
SN - 9781538636121
BT - Proceedings - International Conference Laser Optics 2018, ICLO 2018
PB - Institute of Electrical and Electronics Engineers Inc.
ER -